Contemporary Multidisciplinary Management of Sinonasal Mucosal Melanoma.
head and neck
mucosal melanoma
multidisciplinary
Journal
OncoTargets and therapy
ISSN: 1178-6930
Titre abrégé: Onco Targets Ther
Pays: New Zealand
ID NLM: 101514322
Informations de publication
Date de publication:
2020
2020
Historique:
received:
02
10
2019
accepted:
12
02
2020
entrez:
28
3
2020
pubmed:
28
3
2020
medline:
28
3
2020
Statut:
epublish
Résumé
Sinonasal mucosal melanoma (SNMM) is a rare tumor, comprising less than 10% of sinonasal malignancies. SNMM most frequently occurs in the nasal cavity (70%) and maxillary sinus (14%), typically as black patches. Overall, SNMM harbors a very poor prognosis; 5-year survival is less than 30%. Nasal cavity tumors confer a better prognosis than sinus melanoma. The primary management for SNMM is surgery, when feasible, followed by adjuvant radiotherapy. Recent studies suggest that immunotherapy may confer survival benefit to patients with advanced disease. The multidisciplinary team approach has been shown to optimize treatment, reduce costs, and minimize adverse events, while maximizing the chances for cure.
Identifiants
pubmed: 32214828
doi: 10.2147/OTT.S182580
pii: 182580
pmc: PMC7083634
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
2289-2298Informations de copyright
© 2020 Na’ara et al.
Déclaration de conflit d'intérêts
The authors report no conflicts of interest in this work.
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