The Molecular Control of Calcitonin Receptor Signaling.
Journal
ACS pharmacology & translational science
ISSN: 2575-9108
Titre abrégé: ACS Pharmacol Transl Sci
Pays: United States
ID NLM: 101721411
Informations de publication
Date de publication:
08 Feb 2019
08 Feb 2019
Historique:
received:
14
12
2018
entrez:
29
3
2020
pubmed:
11
1
2019
medline:
11
1
2019
Statut:
epublish
Résumé
The calcitonin receptor (CTR) is a class B G protein-coupled receptor (GPCR) that responds to the peptide hormone calcitonin (CT). CTs are clinically approved for the treatment of bone diseases. We previously reported a 4.1 Å structure of the activated CTR bound to salmon CT (sCT) and heterotrimeric Gs protein by cryo-electron microscopy (Liang, Y.-L.,
Identifiants
pubmed: 32219215
doi: 10.1021/acsptsci.8b00056
pmc: PMC7088896
doi:
Types de publication
Journal Article
Langues
eng
Pagination
31-51Subventions
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/M006883/1
Pays : United Kingdom
Informations de copyright
Copyright © 2019 American Chemical Society.
Déclaration de conflit d'intérêts
The authors declare no competing financial interest.
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