Influence of Positive End-Expiratory Pressure Titration on the Effects of Pronation in Acute Respiratory Distress Syndrome: A Comprehensive Experimental Study.
acute respiratory distress syndrome
positive end-expiratory pressure
prone positioning
titration
ventilator-induced lung injury
Journal
Frontiers in physiology
ISSN: 1664-042X
Titre abrégé: Front Physiol
Pays: Switzerland
ID NLM: 101549006
Informations de publication
Date de publication:
2020
2020
Historique:
received:
06
12
2019
accepted:
17
02
2020
entrez:
1
4
2020
pubmed:
1
4
2020
medline:
1
4
2020
Statut:
epublish
Résumé
Prone position can reduce mortality in acute respiratory distress syndrome (ARDS), but several studies found variable effects on oxygenation and lung mechanics. It is unclear whether different positive end-expiratory pressure (PEEP) titration techniques modify the effect of prone position. We tested, in an animal model of ARDS, if the PEEP titration method may influence the effect of prone position on oxygenation and lung protection. In a crossover study in 10 piglets with a two-hit injury ARDS model, we set the "best PEEP" according to the ARDS Network low-PEEP table (BP
Identifiants
pubmed: 32226390
doi: 10.3389/fphys.2020.00179
pmc: PMC7080860
doi:
Types de publication
Journal Article
Langues
eng
Pagination
179Informations de copyright
Copyright © 2020 Scaramuzzo, Ball, Pino, Ricci, Larsson, Guérin, Pelosi and Perchiazzi.
Références
Am J Respir Crit Care Med. 2006 Jun 1;173(11):1233-9
pubmed: 16556697
J Appl Physiol (1985). 2011 May;110(5):1374-83
pubmed: 21393463
Ann Transl Med. 2018 Oct;6(19):382
pubmed: 30460256
Am J Respir Crit Care Med. 2018 Apr 15;197(8):1018-1026
pubmed: 29323931
JAMA. 2004 Nov 17;292(19):2379-87
pubmed: 15547166
N Engl J Med. 2004 Jul 22;351(4):327-36
pubmed: 15269312
Intensive Care Med. 2016 Oct;42(10):1546-1556
pubmed: 27324241
Acta Anaesthesiol Scand. 2016 Sep;60(8):1131-41
pubmed: 27110871
Crit Care Med. 2017 Mar;45(3):e327-e328
pubmed: 28212229
JAMA. 2009 Nov 11;302(18):1977-84
pubmed: 19903918
Crit Care. 2018 Jan 31;22(1):26
pubmed: 29386048
BMC Res Notes. 2014 Feb 06;7:82
pubmed: 24502320
Intensive Care Med Exp. 2018 Jan 30;6(1):3
pubmed: 29380160
Crit Care Med. 2015 May;43(5):e123-32
pubmed: 25746507
Am J Respir Crit Care Med. 2005 Aug 15;172(4):480-7
pubmed: 15901611
Lab Anim. 2018 Apr;52(2):135-141
pubmed: 28771074
Am Rev Respir Dis. 1982 Nov;126(5):788-91
pubmed: 7149443
N Engl J Med. 2013 Jun 6;368(23):2159-68
pubmed: 23688302
J Appl Physiol (1985). 2012 Jan;112(1):225-36
pubmed: 21960654
Crit Care Med. 2016 Sep;44(9):e854-65
pubmed: 27035236
Am J Respir Crit Care Med. 2014 Feb 15;189(4):494-6
pubmed: 24528322
Intensive Care Med. 2016 Oct;42(10):1567-1575
pubmed: 27620287
Intensive Care Med. 2010 Apr;36(4):585-99
pubmed: 20130832
Intensive Care Med. 1992;18(6):319-21
pubmed: 1469157
Am Rev Respir Dis. 1977 Apr;115(4):559-66
pubmed: 322557
Crit Care Med. 1997 Sep;25(9):1539-44
pubmed: 9295829
JAMA. 2012 Jun 20;307(23):2526-33
pubmed: 22797452
N Engl J Med. 2001 Aug 23;345(8):568-73
pubmed: 11529210
Eur Respir J. 2005 Mar;25(3):534-44
pubmed: 15738300