A comprehensive analysis of methods for assessing polygenic burden on Alzheimer's disease pathology and risk beyond
Alzheimer’s disease
biomarker
imaging genetics
polygenic hazard score
polygenic risk score
Journal
Brain communications
ISSN: 2632-1297
Titre abrégé: Brain Commun
Pays: England
ID NLM: 101755125
Informations de publication
Date de publication:
2020
2020
Historique:
entrez:
1
4
2020
pubmed:
1
4
2020
medline:
1
4
2020
Statut:
ppublish
Résumé
Genome-wide association studies have identified dozens of loci that alter the risk to develop Alzheimer's disease. However, with the exception of the
Identifiants
pubmed: 32226939
doi: 10.1093/braincomms/fcz047
pmc: PMC7100005
mid: EMS86064
doi:
Types de publication
Journal Article
Langues
eng
Pagination
fcz047Subventions
Organisme : Medical Research Council
ID : MR/L501542/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : G0701075
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/L016311/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/L023784/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/M023664/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/N026004/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : G0901254
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/K01417X/1
Pays : United Kingdom
Organisme : Parkinson's UK
ID : G-0907
Pays : United Kingdom
Déclaration de conflit d'intérêts
Competing interests J.M.S. has received research funding and PET tracer from AVID Radiopharmaceuticals (a wholly owned subsidiary of Eli Lilly); has consulted for Roche, Eli Lilly, Biogen and Merck, GE; received royalties from Oxford University Press and Henry Stewart Talks; given education lectures sponsored by Eli Lilly, Biogen and GE; and serves on a Data Safety Monitoring Committee for Axon Neuroscience SE.
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