A core outcome set for future endometriosis research: an international consensus development study.

Biomedical Research Consensus Delphi Technique Endometriosis Endpoint Determination Female Health Personnel Humans Prospective Studies Research Design Research Personnel

Consensus development study core outcome set endometriosis modified Delphi method modified nominal group technique

Journal

BJOG : an international journal of obstetrics and gynaecology

ISSN: 1471-0528

Titre abrégé: BJOG

Pays: England

ID NLM: 100935741

Informations de publication

Date de publication:
Jul 2020

Historique:

accepted: 28 01 2020

pubmed: 1 4 2020

medline: 1 7 2020

entrez: 1 4 2020

Statut: ppublish

Résumé

To develop a core outcome set for endometriosis. Consensus development study. International. One hundred and sixteen healthcare professionals, 31 researchers and 206 patient representatives. Modified Delphi method and modified nominal group technique. The final core outcome set includes three core outcomes for trials evaluating potential treatments for pain and other symptoms associated with endometriosis: overall pain; improvement in the most troublesome symptom; and quality of life. In addition, eight core outcomes for trials evaluating potential treatments for infertility associated with endometriosis were identified: viable intrauterine pregnancy confirmed by ultrasound; pregnancy loss, including ectopic pregnancy, miscarriage, stillbirth and termination of pregnancy; live birth; time to pregnancy leading to live birth; gestational age at delivery; birthweight; neonatal mortality; and major congenital abnormalities. Two core outcomes applicable to all trials were also identified: adverse events and patient satisfaction with treatment. Using robust consensus science methods, healthcare professionals, researchers and women with endometriosis have developed a core outcome set to standardise outcome selection, collection and reporting across future randomised controlled trials and systematic reviews evaluating potential treatments for endometriosis. TWEETABLE ABSTRACT: @coreoutcomes for future #endometriosis research have been developed @jamesmnduffy.

Identifiants

DOI: 10.1111/1471-0528.16157 PMID: 32227676

pubmed: 32227676

doi: 10.1111/1471-0528.16157

doi:

Types de publication

Journal Article Systematic Review

Langues

eng

Sous-ensembles de citation

Pagination

967-974

Subventions

Organisme : Department of Health

ID : DRF-2014-07-051

Pays : United Kingdom

Organisme : Chief Scientist Office

ID : TCS/18/43

Pays : United Kingdom

Organisme : Catalyst Fund

Organisme : Endometriosis Millennium Fund

Investigateurs

Jane P Daniels (JP)

Arianne C Lim (AC)

Katie Edmonds (K)

Claire E MacLean (CE)

Amy C Appleton (AC)

Sarah Skelton (S)

Dominic L Byrne (DL)

Rebecca K White (RK)

Margarida Sardo (M)

Rebecca C Fowles (RC)

Baris Ata (B)

Sarah A Richatd (SA)

Casandra C Puig Ybanez (CC)

Matthew C Peterson (MC)

Jasmin L Elms (JL)

Ann Parks (A)

Bianca L F De Bie Rocks (BLF)

Jodie C Roe (JC)

Ruby Doran (R)

Marcello Ceccaroni (M)

Ceu A Ferreira (CA)

Sofia Dias (S)

Tracey Pinnington (T)

Paula Laupa-Santiago (P)

Marie C Turner (MC)

Anneke M F Schreurs (AMF)

Eleanor Baggot (E)

Razvan V Socolov (RV)

Menem Yossry (M)

Tania M Hodges (TM)

Marina W P Barbossa (MWP)

Târgu Mures (T)

Tracy L Lytwyn (TL)

Sophia E L Egan-Reid (SEL)

Susanna C L Devlin (SCL)

Kira S Crees (KS)

Bethany C Baldwin (BC)

James R Scott (JR)

Amy K Gravolin (AK)

Errin F Chapman (EF)

Stephanie N Bartley (SN)

Alicia J Hamilton (AJ)

Kirstie J Thorpe (KJ)

Denise M Carmody (DM)

Joanna Eyeson (J)

Madeleine D Davis (MD)

Jo Henry (J)

Mike Armour (M)

Presley Y F V Cummings (PYFV)

Lisa A Cook (LA)

Informations de copyright

Références

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