Current states of prevention of drug-induced gastroduodenal ulcer in real clinical practice: a cross-sectional study.

gastroduodenal ulcer low-dose aspirin non-steroidal anti-inflammatory drugs prevention

Journal

Journal of clinical biochemistry and nutrition
ISSN: 0912-0009
Titre abrégé: J Clin Biochem Nutr
Pays: Japan
ID NLM: 8700907

Informations de publication

Date de publication:
Mar 2020
Historique:
received: 26 07 2019
accepted: 04 12 2019
entrez: 2 4 2020
pubmed: 2 4 2020
medline: 2 4 2020
Statut: ppublish

Résumé

Non-steroidal anti-inflammatory drugs (NSAIDs) or low-dose aspirin (LDA) are the most common causes of drug-induced gastroduodenal ulcer and We investigated preventive treatment with use of concomitant anti-ulcer drugs and the clinical features of gastroduodenal ulcer in cases treated with these drugs. Patients with gastroduodenal ulcer and patients with bleeding were classified into 3 groups: LDA, non-aspirin NSAIDs, and those taking neither aspirin nor NSAIDs. Chronological changes over the past 16 years (1st-5th period) were investigated. The status of prevention of ulcer and clinical features were examined. From January 2002 to December 2018, the ratio of all patients taking NSAIDs and LDA increased significantly until 3rd period (

Identifiants

pubmed: 32231413
doi: 10.3164/jcbn.19-66
pii: DN/JST.JSTAGE/jcbn/19-66
pmc: PMC7093299
doi:

Types de publication

Journal Article

Langues

eng

Pagination

158-162

Informations de copyright

Copyright © 2020 JCBNCopyright © 2020 JCBN.

Déclaration de conflit d'intérêts

No potential conflicts of interest were disclosed.

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Auteurs

Junichi Iwamoto (J)

Department of Gastroenterology, Tokyo Medical University Ibaraki Medical Center, Chuo 3-20-1, Ami, Inashiki, Ibaraki 300-0395, Japan.

Masashi Murakami (M)

Department of Gastroenterology, Tokyo Medical University Ibaraki Medical Center, Chuo 3-20-1, Ami, Inashiki, Ibaraki 300-0395, Japan.

Tadakuni Monma (T)

Department of Gastroenterology, Tokyo Medical University Ibaraki Medical Center, Chuo 3-20-1, Ami, Inashiki, Ibaraki 300-0395, Japan.

Hajime Ueda (H)

Department of Gastroenterology, Tokyo Medical University Ibaraki Medical Center, Chuo 3-20-1, Ami, Inashiki, Ibaraki 300-0395, Japan.

Makoto Tamamushi (M)

Department of Gastroenterology, Tokyo Medical University Ibaraki Medical Center, Chuo 3-20-1, Ami, Inashiki, Ibaraki 300-0395, Japan.

Naoki Konishi (N)

Department of Gastroenterology, Tokyo Medical University Ibaraki Medical Center, Chuo 3-20-1, Ami, Inashiki, Ibaraki 300-0395, Japan.

Sho-Ichiro Yara (SI)

Department of Gastroenterology, Tokyo Medical University Ibaraki Medical Center, Chuo 3-20-1, Ami, Inashiki, Ibaraki 300-0395, Japan.

Takeshi Hirayama (T)

Department of Gastroenterology, Tokyo Medical University Ibaraki Medical Center, Chuo 3-20-1, Ami, Inashiki, Ibaraki 300-0395, Japan.

Tadashi Ikegami (T)

Department of Gastroenterology, Tokyo Medical University Ibaraki Medical Center, Chuo 3-20-1, Ami, Inashiki, Ibaraki 300-0395, Japan.

Akira Honda (A)

Department of Gastroenterology, Tokyo Medical University Ibaraki Medical Center, Chuo 3-20-1, Ami, Inashiki, Ibaraki 300-0395, Japan.
Joint Research Center, Tokyo Medical University Ibaraki Medical Center, Chuo 3-20-1, Ami, Inashiki, Ibaraki 300-0395, Japan.

Yuji Mizokami (Y)

Department of Gastroenterology, University of Tsukuba, 1-1-1, Tennodai, Tsukuba, Ibaraki 305-8577, Japan.

Classifications MeSH