Predicting Difficult Laparoscopic Total Mesorectal Excision for Locally-advanced Mid-low Rectal Cancer: The
Aged
Chemoradiotherapy
Female
Humans
Laparoscopy
/ methods
Magnetic Resonance Imaging
/ methods
Male
Middle Aged
Neoadjuvant Therapy
Neoplasm Recurrence, Local
/ diagnostic imaging
Rectal Neoplasms
/ diagnostic imaging
Rectum
/ diagnostic imaging
Surgery, Computer-Assisted
/ methods
Survival Analysis
Predictive score
laparoscopy
locally advanced rectal cancer
total mesorectal excision
Journal
Anticancer research
ISSN: 1791-7530
Titre abrégé: Anticancer Res
Pays: Greece
ID NLM: 8102988
Informations de publication
Date de publication:
Apr 2020
Apr 2020
Historique:
received:
14
02
2020
revised:
24
02
2020
accepted:
27
02
2020
entrez:
3
4
2020
pubmed:
3
4
2020
medline:
11
4
2020
Statut:
ppublish
Résumé
The European MRI and Rectal Cancer Surgery (EuMaRCS) score was proposed to identify preoperatively difficult laparoscopic total mesorectal excision (L-TME) for locally advanced rectal cancer (LARC). This study aimed to test EuMaRCS's validity. Data were retrieved from a European multicenter database, including patients with mid/low LARC, treated with neoadjuvant chemoradiation therapy and L-TME with primary anastomosis. The EuMaRCS score was calculated on: BMI>30 (3 points), interspinous distance<96.4 mm (2 points), ymrT stage≥T3b (4 points), and male sex (1 point). The sample was composed of 141 patients, of whom 23 (16.3%) had a difficult L-TME. The EuMaRCS score demonstrated high accuracy in predicting difficult surgery (AROC: 0.806, 95%CI=0.72-0.88), with a cut-off >3 being associated with the best balance in sensitivity (82.6%) and specificity (66.1%). The EuMaRCS score represents a validated tool to predict preoperatively difficult L-TME in LARC patients.
Sections du résumé
BACKGROUND/AIM
OBJECTIVE
The European MRI and Rectal Cancer Surgery (EuMaRCS) score was proposed to identify preoperatively difficult laparoscopic total mesorectal excision (L-TME) for locally advanced rectal cancer (LARC). This study aimed to test EuMaRCS's validity.
PATIENTS AND METHODS
METHODS
Data were retrieved from a European multicenter database, including patients with mid/low LARC, treated with neoadjuvant chemoradiation therapy and L-TME with primary anastomosis. The EuMaRCS score was calculated on: BMI>30 (3 points), interspinous distance<96.4 mm (2 points), ymrT stage≥T3b (4 points), and male sex (1 point).
RESULTS
RESULTS
The sample was composed of 141 patients, of whom 23 (16.3%) had a difficult L-TME. The EuMaRCS score demonstrated high accuracy in predicting difficult surgery (AROC: 0.806, 95%CI=0.72-0.88), with a cut-off >3 being associated with the best balance in sensitivity (82.6%) and specificity (66.1%).
CONCLUSION
CONCLUSIONS
The EuMaRCS score represents a validated tool to predict preoperatively difficult L-TME in LARC patients.
Identifiants
pubmed: 32234900
pii: 40/4/2079
doi: 10.21873/anticanres.14166
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2079-2087Informations de copyright
Copyright© 2020, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.