FlexPro MD®, a Combination of Krill Oil, Astaxanthin and Hyaluronic Acid, Reduces Pain Behavior and Inhibits Inflammatory Response in Monosodium Iodoacetate-Induced Osteoarthritis in Rats.
Animals
Cartilage, Articular
/ pathology
Dietary Supplements
Disease Models, Animal
Euphausiacea
/ chemistry
Hyaluronic Acid
/ administration & dosage
Inflammation
Iodoacetates
/ adverse effects
Male
Osteoarthritis
/ chemically induced
Pain
/ drug therapy
Phytotherapy
Plant Oils
/ administration & dosage
Rats, Sprague-Dawley
Treatment Outcome
Xanthophylls
/ administration & dosage
FlexPro MD
astaxanthin
hyaluronic acid
inflammation
krill oil
osteoarthritis
pain
Journal
Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595
Informations de publication
Date de publication:
30 Mar 2020
30 Mar 2020
Historique:
received:
17
02
2020
revised:
24
03
2020
accepted:
26
03
2020
entrez:
3
4
2020
pubmed:
3
4
2020
medline:
29
12
2020
Statut:
epublish
Résumé
Osteoarthritis (OA) is a degenerative joint disease and a leading cause of adult disability. Since there is no cure for OA and no effective treatment to slow its progression, current pharmacologic treatments, such as analgesics and non-steroidal anti-inflammatory drugs (NSAIDs), only alleviate symptoms, such as pain and inflammation, but do not inhibit the disease process. Moreover, chronic intake of these drugs may result in severe adverse effects. For these reasons, patients have turned to the use of various complementary and alternative approaches, including diverse dietary supplements and nutraceuticals, in an effort to improve symptoms and manage or slow disease progression. The present study was conducted to evaluate the anti-osteoarthritic effects of FlexPro MD
Identifiants
pubmed: 32235618
pii: nu12040956
doi: 10.3390/nu12040956
pmc: PMC7230382
pii:
doi:
Substances chimiques
Iodoacetates
0
Plant Oils
0
Xanthophylls
0
astaxanthine
8XPW32PR7I
Hyaluronic Acid
9004-61-9
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : National Research Foundation of Korea
ID : MRC, 2017R1A5A2015541
Organisme : Chungbuk National University
ID : 2019101027
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