Asymmetric trifluoromethylthiolation of azlactones under chiral phase transfer catalysis.
Journal
Organic & biomolecular chemistry
ISSN: 1477-0539
Titre abrégé: Org Biomol Chem
Pays: England
ID NLM: 101154995
Informations de publication
Date de publication:
15 04 2020
15 04 2020
Historique:
pubmed:
3
4
2020
medline:
3
4
2020
entrez:
3
4
2020
Statut:
ppublish
Résumé
The first enantioselective method for the installation of the SCF3 group at the C-4 position of azlactones is described in the present communication under quinidinium phase transfer catalysis. The higher performance of substrates containing electron-rich 2-aryl groups at the azlactone was rationalized using DFT calculations.
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM