PBX1 expression in uterine natural killer cells drives fetal growth.

Animals Decidua / metabolism Female Fetal Development Humans Intercellular Signaling Peptides and Proteins Killer Cells, Natural Mice Pregnancy Uterus

Journal

Science translational medicine
ISSN: 1946-6242
Titre abrégé: Sci Transl Med
Pays: United States
ID NLM: 101505086

Informations de publication

Date de publication:
01 04 2020
Historique:
received: 28 02 2019
revised: 19 11 2019
accepted: 12 02 2020
entrez: 3 4 2020
pubmed: 3 4 2020
medline: 1 6 2021
Statut: ppublish

Résumé

Abundant decidual natural killer (dNK) cells at the maternal-fetal interface are important during early pregnancy. However, functional subsets of dNK cells remain poorly understood. We describe a CD49a

Identifiants

DOI: 10.1126/scitranslmed.aax1798 PMID: 32238574
pubmed: 32238574
pii: 12/537/eaax1798
doi: 10.1126/scitranslmed.aax1798
pii:
doi:

Substances chimiques

Intercellular Signaling Peptides and Proteins 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

Auteurs

Yonggang Zhou (Y)

Division of Molecular Medicine, Hefei National Laboratory for Physical Sciences at Microscale, The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027, China.
Institute of Immunology, University of Science and Technology of China, Hefei, Anhui 230027, China.
First Affiliated Hospital, University of Science and Technology of China, Hefei, Anhui 230026, China.
ORCID: 0000-0003-2905-3213

Binqing Fu (B)

Division of Molecular Medicine, Hefei National Laboratory for Physical Sciences at Microscale, The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027, China. ustcwhm@ustc.edu.cn tzg@ustc.edu.cn fbq@ustc.edu.cn.
Institute of Immunology, University of Science and Technology of China, Hefei, Anhui 230027, China.
ORCID: 0000-0002-7713-0001

Xiuxiu Xu (X)

Division of Molecular Medicine, Hefei National Laboratory for Physical Sciences at Microscale, The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027, China.
Institute of Immunology, University of Science and Technology of China, Hefei, Anhui 230027, China.

Jinghe Zhang (J)

Division of Molecular Medicine, Hefei National Laboratory for Physical Sciences at Microscale, The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027, China.
Institute of Immunology, University of Science and Technology of China, Hefei, Anhui 230027, China.

Xianhong Tong (X)

First Affiliated Hospital, University of Science and Technology of China, Hefei, Anhui 230026, China.

Yanshi Wang (Y)

First Affiliated Hospital, University of Science and Technology of China, Hefei, Anhui 230026, China.

Zhongjun Dong (Z)

School of Medicine, Tsinghua University, Beijing 100086, China.

Xiaoren Zhang (X)

CAS Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 200025, China.

Nan Shen (N)

Shanghai Institute of Rheumatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200001, China.
ORCID: 0000-0002-5875-4417

Yiwen Zhai (Y)

Center for Genetic and Prenatal Diagnosis, Department of Gynecology and Obstetrics, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China.
ORCID: 0000-0002-6149-1961

Xiangdong Kong (X)

Center for Genetic and Prenatal Diagnosis, Department of Gynecology and Obstetrics, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China.
ORCID: 0000-0003-4322-914X

Rui Sun (R)

Division of Molecular Medicine, Hefei National Laboratory for Physical Sciences at Microscale, The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027, China.
Institute of Immunology, University of Science and Technology of China, Hefei, Anhui 230027, China.

Zhigang Tian (Z)

Division of Molecular Medicine, Hefei National Laboratory for Physical Sciences at Microscale, The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027, China. ustcwhm@ustc.edu.cn tzg@ustc.edu.cn fbq@ustc.edu.cn.
Institute of Immunology, University of Science and Technology of China, Hefei, Anhui 230027, China.
ORCID: 0000-0002-5512-6378

Haiming Wei (H)

Division of Molecular Medicine, Hefei National Laboratory for Physical Sciences at Microscale, The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027, China. ustcwhm@ustc.edu.cn tzg@ustc.edu.cn fbq@ustc.edu.cn.
Institute of Immunology, University of Science and Technology of China, Hefei, Anhui 230027, China.
ORCID: 0000-0002-1675-6502

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › PBX1 expression in uterine natural killer...
questionsmedicales.fr › Structures de l'embryon › Placenta › Caduques › PBX1 expression in uterine natural killer...
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques de la reproduction › Reproduction › Développement embryonnaire et foetal › Développement foetal › PBX1 expression in uterine natural killer...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › PBX1 expression in uterine natural killer...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › PBX1 expression in uterine natural killer...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › Cellules tueuses naturelles › PBX1 expression in uterine natural killer...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › PBX1 expression in uterine natural killer...
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques de la reproduction › Reproduction › Grossesse › PBX1 expression in uterine natural killer...
questionsmedicales.fr › Appareil urogénital › Système génital › Système génital de la femme › Utérus › PBX1 expression in uterine natural killer...