Effects of Diluent Volume and Administration Time on the Incidence of Anaphylaxis Following Docetaxel Therapy in Breast Cancer.
Administration, Intravenous
Adult
Aged
Anaphylaxis
/ chemically induced
Antineoplastic Agents
/ administration & dosage
Breast Neoplasms
/ drug therapy
Docetaxel
/ administration & dosage
Drug Administration Schedule
Drug Hypersensitivity
/ etiology
Female
Humans
Incidence
Leukocyte Count
Middle Aged
Risk Factors
administration time
anaphylaxis
diluent volume
docetaxel
hypersensitivity reaction
Journal
Biological & pharmaceutical bulletin
ISSN: 1347-5215
Titre abrégé: Biol Pharm Bull
Pays: Japan
ID NLM: 9311984
Informations de publication
Date de publication:
2020
2020
Historique:
entrez:
3
4
2020
pubmed:
3
4
2020
medline:
1
12
2020
Statut:
ppublish
Résumé
Hypersensitivity reactions, including anaphylaxis, are common side effects associated with docetaxel treatment in breast cancer patients. However, preventive measures have not yet been established. In this study, we retrospectively analyzed the risk factors for developing anaphylaxis in 182 female breast cancer patients treated with docetaxel. We found that 6.6% of all patients (n = 12) experienced anaphylaxis. Multivariate analyses indicated that concentration of docetaxel higher than 0.275 mg/m
Identifiants
pubmed: 32238707
doi: 10.1248/bpb.b19-00876
doi:
Substances chimiques
Antineoplastic Agents
0
Docetaxel
15H5577CQD
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM