Ultrasound can differentiate inclusion body myositis from disease mimics.
diagnosis
echogenicity
inclusion body myositis
neuromuscular disorders
quantitative muscle ultrasound
Journal
Muscle & nerve
ISSN: 1097-4598
Titre abrégé: Muscle Nerve
Pays: United States
ID NLM: 7803146
Informations de publication
Date de publication:
06 2020
06 2020
Historique:
received:
14
10
2019
revised:
20
03
2020
accepted:
27
03
2020
pubmed:
3
4
2020
medline:
30
7
2020
entrez:
3
4
2020
Statut:
ppublish
Résumé
The diagnosis of inclusion body myositis (IBM) can be challenging, and its presentation can be confused with other forms of myositis or neuromuscular disorders. In this study we evaluate the ability of quantitative muscle ultrasound to differentiate between IBM and mimicking diseases. Patients 50 years of age and older were included from two specialty centers. Muscle echogenicity and muscle thickness of four characteristically involved muscles in IBM were measured and compared with polymyositis (PM)/dermatomyositis (DM), other neuromuscular disorders, and healthy controls. Echogenicity was higher and muscle thickness generally lower in all four muscles in IBM compared with PM/DM and normal controls. When comparing IBM with the comparator groups, the flexor digitorum profundus was the most discriminative muscle. Ultrasound appears to be a good test to differentiate established IBM from PM/DM and neuromuscular controls, with value as a diagnostic tool for IBM.
Identifiants
pubmed: 32239702
doi: 10.1002/mus.26875
pmc: PMC7317807
doi:
Types de publication
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
783-788Subventions
Organisme : NIAMS NIH HHS
ID : K23 AR075898
Pays : United States
Informations de copyright
© 2020 The Authors. Muscle & Nerve published by Wiley Periodicals, Inc.
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