Multicenter Ozone Study in oldEr Subjects (MOSES): Part 2. Effects of Personal and Ambient Concentrations of Ozone and Other Pollutants on Cardiovascular and Pulmonary Function.
Journal
Research report (Health Effects Institute)
ISSN: 1041-5505
Titre abrégé: Res Rep Health Eff Inst
Pays: United States
ID NLM: 8812230
Informations de publication
Date de publication:
Mar 2020
Mar 2020
Historique:
entrez:
3
4
2020
pubmed:
3
4
2020
medline:
27
10
2021
Statut:
ppublish
Résumé
The Multicenter Ozone Study of oldEr Subjects (MOSES) was a multi-center study evaluating whether short-term controlled exposure of older, healthy individuals to low levels of ozone (O MOSES 1 was conducted at three clinical centers (University of California San Francisco, University of North Carolina, and University of Rochester Medical Center) and included healthy volunteers 55 to 70 years of age. Consented participants who successfully completed the screening and training sessions were enrolled in the study. All three clinical centers adhered to common standard operating procedures and used common tracking and data forms. Each subject was scheduled to participate in a total of 11 visits: screening visit, training visit, and three sets of exposure visits consisting of the pre-exposure day, the exposure day, and the post-exposure day. After completing the pre-exposure day, subjects spent the night in a nearby hotel. On exposure days, the subjects were exposed for 3 hours in random order to 0 ppb O In MOSES Part 2 (MOSES 2), we used a longitudinal panel study design, cardiopulmonary biomarker data from MOSES 1, passive cumulative personal exposure samples (PES) of O Ambient pollutant concentrations at each site were low and were regularly below the National Ambient Air Quality Standard levels. In Aim 1, the controlled O As hypothesized for Aim 3, increased ambient O Similar Aim 3 and Aim 4 patterns were observed for FEV Our previous MOSES 1 findings of controlled O
Identifiants
pubmed: 32239870
pii: Res Rep Health Eff Inst. 2020 Mar;(192, Pt 2):1-90.
pmc: PMC7325421
pii:
Substances chimiques
Air Pollutants
0
Biomarkers
0
Ozone
66H7ZZK23N
C-Reactive Protein
9007-41-4
Nitrogen Dioxide
S7G510RUBH
Types de publication
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Technical Report
Langues
eng
Sous-ensembles de citation
IM
Pagination
1-90Informations de copyright
© 2020 Health Effects Institute. All rights reserved.
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