Effects of available phosphorus source and concentration on performance and expression of sodium phosphate type IIb cotransporter, vitamin D-1α-hydroxylase, and vitamin D-24-hydroxylase mRNA in broiler chicks.
Animal Feed
/ analysis
Animals
Avian Proteins
/ genetics
Biological Availability
Calcium Phosphates
/ administration & dosage
Chickens
/ genetics
Diet
/ veterinary
Dietary Supplements
/ analysis
Dose-Response Relationship, Drug
Duodenum
/ metabolism
Kidney
/ metabolism
Nanoparticles
/ administration & dosage
Phosphorus, Dietary
/ administration & dosage
RNA, Messenger
/ metabolism
Random Allocation
Sodium-Phosphate Cotransporter Proteins, Type IIb
/ genetics
Steroid Hydroxylases
/ genetics
Vitamin D3 24-Hydroxylase
/ genetics
dicalcium phosphate
nanophosphate
phosphate transporter
vitamin D hydroxylase
Journal
Poultry science
ISSN: 1525-3171
Titre abrégé: Poult Sci
Pays: England
ID NLM: 0401150
Informations de publication
Date de publication:
Apr 2020
Apr 2020
Historique:
received:
19
08
2019
revised:
26
11
2019
accepted:
10
12
2019
entrez:
4
4
2020
pubmed:
4
4
2020
medline:
21
10
2020
Statut:
ppublish
Résumé
This experiment was conducted to examine the effect of 2 phosphorus (P) sources on broiler performance to day 14. The P bioavailability was estimated using bird performance and tibia ash measurements, whereas P digestibility, intestinal P transporter, kidney vitamin D-1α-hydroxylase, and vitamin D-24-hydroxylase mRNA abundances were also determined. Slope regression analysis was used to determine the bioavailability of dicalcium phosphate (Dical P) and nanocalcium phosphate (Nano P) with dietary available P (AvP) set to 0.20% P (control) using AvP from the major ingredients and Dical P. The experimental treatments were achieved by supplementation with either Dical P or Nano P to generate 0.24, 0.28, 0.32, and 0.36% AvP. A total of 648-day-old unsexed broiler chicks were divided into 72 birds per treatment (8 replicate cages of 9 birds). Slope regression analysis showed positive linear relationships between BW, feed intake (FI), tibia ash weight (TAW), and tibia ash percentage (TAP) with dietary Dical P and Nano P levels. Comparisons between regression slopes for Dical P and Nano P fed birds were not significantly different for BW, feed intake, tibia ash weight, and tibia ash percentage, indicating similar P bioavailability from Dical P and Nano P. There were interactions between P source and AvP for feed efficiency (FE) and apparent ileal P digestibility (AIPD). Dicalcium phosphate had greater FE than Nano P at 0.28% AvP and greater AIPD than Nano P at 0.24% AvP. The addition of AvP from Dical P and Nano P resulted in reduced sodium phosphate cotransporter mRNA abundance in the duodenum in a dose-dependent response. In the kidney, vitamin D-1α-hydroxylase mRNA abundance was greater at 0.36% Nano P compared with control, but there was no difference with Dical P. There was no difference in vitamin D-24-hydroxylase mRNA abundance between control and supplementation with Nano P or Dical P. In conclusion, Nano P and Dical P had the same bioavailability but had different effects on gene expression.
Identifiants
pubmed: 32241462
pii: S0032-5791(20)30008-0
doi: 10.1016/j.psj.2019.12.035
pmc: PMC7587676
pii:
doi:
Substances chimiques
Avian Proteins
0
Calcium Phosphates
0
Phosphorus, Dietary
0
RNA, Messenger
0
Sodium-Phosphate Cotransporter Proteins, Type IIb
0
Steroid Hydroxylases
EC 1.14.-
vitamin D 1-alpha hydroxylase
EC 1.14.-
Vitamin D3 24-Hydroxylase
EC 1.14.15.16
calcium phosphate, dibasic, dihydrate
O7TSZ97GEP
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1822-1831Informations de copyright
Copyright © 2019 The Authors. Published by Elsevier Inc. All rights reserved.
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