Polyvinyl chloride (PVC) plastic fragments release Pb additives that are bioavailable in zebrafish.

Animals Lead Plastics Polyvinyl Chloride Water Pollutants, Chemical Zebrafish
Metallothionein Microplastic Pb Polyvinyl chloride Zebrafish

Journal

Environmental pollution (Barking, Essex : 1987)
ISSN: 1873-6424
Titre abrégé: Environ Pollut
Pays: England
ID NLM: 8804476

Informations de publication

Date de publication:
Aug 2020
Historique:
received: 22 01 2020
revised: 11 03 2020
accepted: 18 03 2020
pubmed: 4 4 2020
medline: 11 7 2020
entrez: 4 4 2020
Statut: ppublish

Résumé

Plastic polymers such as polyvinyl chloride (PVC) may contain chemical additives, such as lead (Pb), that are leachable in aqueous solution. The fragmentation into microplastics (MPs) of plastics such as PVC may facilitate desorption of chemical additives and increase exposure of aquatic animals. In this study, the role of chemical additives in the aqueous toxicity of PVC, high-density polyethylene (HDPE) and polyethylene terephthalate (PET) MPs were investigated in early-life stage zebrafish (Danio rerio) by assessment of changes in expression of biomarkers. Exposure of zebrafish larvae to PVC for 24 h increased expression of metallothionein 2 (mt2), a metal-binding protein, but no changes in expression of biomarkers of estrogenic (vtg1) or organic (cyp1a) contaminants were observed. HDPE and PET caused no changes in expression of any biomarkers. A filtered leachate of the PVC also caused a significant increase in expression of mt2 and indicated that a desorbed metal additive likely elicited the response in zebrafish. Metal release was confirmed by acid-washing the MPs which mitigated the response in mt2. Metal analysis showed Pb leached from PVC into water during exposures; at 500 mg PVC L

Identifiants

DOI: 10.1016/j.envpol.2020.114422 PMID: 32244159
pubmed: 32244159
pii: S0269-7491(20)30521-2
doi: 10.1016/j.envpol.2020.114422
pii:
doi:

Substances chimiques

Plastics 0
Water Pollutants, Chemical 0
Lead 2P299V784P
Polyvinyl Chloride 9002-86-2

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

114422

Informations de copyright

Copyright © 2020 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

David Boyle (D)

The School of Energy, Geoscience, Infrastructure and Society, Heriot-Watt University, Edinburgh, EH14 4AS, UK; School of Biological and Marine Sciences, University of Plymouth, Plymouth, PL4 8AA, UK.

Ana I Catarino (AI)

The School of Energy, Geoscience, Infrastructure and Society, Heriot-Watt University, Edinburgh, EH14 4AS, UK; Vlaams Instituut voor de Zee, Flanders Marine Institute, Wandelaarkaai 7, 8400, Ostend, Belgium.

Nathaniel J Clark (NJ)

School of Biological and Marine Sciences, University of Plymouth, Plymouth, PL4 8AA, UK.

Theodore B Henry (TB)

The School of Energy, Geoscience, Infrastructure and Society, Heriot-Watt University, Edinburgh, EH14 4AS, UK; Department of Forestry, Wildlife and Fisheries, and Center for Environmental Biotechnology, The University of Tennessee, Knoxville, TN, USA. Electronic address: t.henry@hw.ac.uk.

Articles similaires

Evaluating the efficacy of telesurgery with dual console SSI Mantra Surgical Robotic System: experiment on animal model and clinical trials.

Sudhir Prem Srivastava, Vishwajyoti Pascual Srivastava, Avinesh Singh et al.
1.00
Robotic Surgical Procedures Animals Humans Telemedicine Models, Animal

Odour generalisation and detection dog training.

Lyn Caldicott, Thomas W Pike, Helen E Zulch et al.
1.00
Animals Odorants Dogs Generalization, Psychological Smell

FBXO22 inhibits colitis and colorectal carcinogenesis by regulating the degradation of the S2448-phosphorylated form of mTOR.

Minle Li, Xuan Chen, Pengfei Qu et al.
1.00
Animals TOR Serine-Threonine Kinases Colorectal Neoplasms Colitis Mice

Use of organic material provided by an automatic enrichment device by weaner pigs and its influence on tail lesions.

Philipp Heseker, Jeanette Probst, Stefanie Ammer et al.
1.00
Animals Tail Swine Behavior, Animal Animal Husbandry

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Polyvinyl chloride (PVC) plastic fragments...
questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Métaux lourds › Plomb › Polyvinyl chloride (PVC) plastic fragments...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomédicaux et dentaires › Polymères › Matières plastiques › Polyvinyl chloride (PVC) plastic fragments...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomédicaux et dentaires › Polymères › Matières plastiques › Polyvinyles › Poly(chlorure de vinyle) › Polyvinyl chloride (PVC) plastic fragments...
questionsmedicales.fr › Actions chimiques et utilisations › Actions toxiques › Polluants environnementaux › Polluants de l'eau › Polluants chimiques de l'eau › Polyvinyl chloride (PVC) plastic fragments...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Poissons › Cypriniformes › Cyprinidae › Danio zébré › Polyvinyl chloride (PVC) plastic fragments...