Aspirin: A Suicide Inhibitor of Carbonic Anhydrase II.

Aspirin / pharmacology Carbonic Anhydrase II / antagonists & inhibitors Catalytic Domain Enzyme Inhibitors / pharmacology Kinetics Models, Molecular
Aspirin X-ray crystallography carbonic anhydrase esterase salicylic acid

Journal

Biomolecules
ISSN: 2218-273X
Titre abrégé: Biomolecules
Pays: Switzerland
ID NLM: 101596414

Informations de publication

Date de publication:
31 03 2020
Historique:
received: 14 03 2020
revised: 25 03 2020
accepted: 30 03 2020
entrez: 5 4 2020
pubmed: 5 4 2020
medline: 30 3 2021
Statut: epublish

Résumé

Carbonic anhydrase II (CAII) is a metalloenzyme that catalyzes the reversible hydration/dehydration of CO

Identifiants

DOI: 10.3390/biom10040527 PMID: 32244293 PMC: PMC7226357
pubmed: 32244293
pii: biom10040527
doi: 10.3390/biom10040527
pmc: PMC7226357
pii:
doi:

Substances chimiques

Enzyme Inhibitors 0
Carbonic Anhydrase II EC 4.2.1.-
Aspirin R16CO5Y76E

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Références

J Comput Chem. 2004 Oct;25(13):1605-12
pubmed: 15264254
Acta Crystallogr F Struct Biol Commun. 2019 Mar 1;75(Pt 3):166-170
pubmed: 30839290
Nat Rev Cancer. 2016 Mar;16(3):173-86
pubmed: 26868177
Otolaryngol Head Neck Surg. 2015 Jan;152(1):23-41
pubmed: 25358343
Biochem Biophys Res Commun. 1964;14:256-61
pubmed: 4953741
Proteins. 1988;4(4):274-82
pubmed: 3151019
Subcell Biochem. 2014;75:9-30
pubmed: 24146372
J Med Chem. 2018 Jul 26;61(14):6328-6338
pubmed: 29962205
Bioorg Med Chem. 2013 Nov 15;21(22):7210-5
pubmed: 24090602
J Med Chem. 2018 Jun 28;61(12):5380-5394
pubmed: 29851481
Subcell Biochem. 2014;75:349-59
pubmed: 24146387
Acta Crystallogr D Biol Crystallogr. 2011 Apr;67(Pt 4):235-42
pubmed: 21460441
Biomed Res Int. 2018 Jun 28;2018:4548353
pubmed: 30050931
Int J Mol Sci. 2016 Jul 16;17(7):
pubmed: 27438828
Eur J Biochem. 1975 Nov 1;59(1):253-9
pubmed: 1249
J Pharm Sci. 1972 Mar;61(3):379-85
pubmed: 5013373
Acta Crystallogr D Biol Crystallogr. 2015 Aug;71(Pt 8):1745-56
pubmed: 26249355
Biochemistry. 2010 Jan 19;49(2):249-51
pubmed: 20000378
J Med Chem. 2020 Jan 9;63(1):321-333
pubmed: 31794211
Oxid Med Cell Longev. 2017;2017:3132063
pubmed: 29090039
Gene. 1992 Aug 1;117(1):113-7
pubmed: 1644301
Acta Crystallogr D Biol Crystallogr. 2004 Dec;60(Pt 12 Pt 1):2126-32
pubmed: 15572765
Bioorg Med Chem. 2008 Aug 1;16(15):7424-8
pubmed: 18579385
Acta Crystallogr D Biol Crystallogr. 2010 Feb;66(Pt 2):213-21
pubmed: 20124702
J Enzyme Inhib Med Chem. 2019 Dec;34(1):117-123
pubmed: 30362384
Acta Crystallogr D Biol Crystallogr. 2010 Feb;66(Pt 2):125-32
pubmed: 20124692
J Biol Chem. 1971 Apr 25;246(8):2561-73
pubmed: 4994926
Molecules. 2017 Dec 22;23(1):
pubmed: 29271882
J Enzyme Inhib Med Chem. 2015 Dec;30(6):955-60
pubmed: 25775095
Acta Crystallogr D Biol Crystallogr. 2013 Jul;69(Pt 7):1204-14
pubmed: 23793146
J Biol Chem. 2008 Nov 7;283(45):30766-71
pubmed: 18768466
Anal Chem. 2002 Aug 1;74(15):3772-6
pubmed: 12175165
Am J Physiol. 1983 Jul;245(1):F110-8
pubmed: 6408932
Biomed Pharmacother. 2017 Nov;95:656-661
pubmed: 28881293
J Chem Inf Model. 2011 Oct 24;51(10):2778-86
pubmed: 21919503
Drugs. 2017 Nov;77(17):1819-1831
pubmed: 29039130
Acta Crystallogr D Biol Crystallogr. 1994 Jan 1;50(Pt 1):101-4
pubmed: 15299482

Auteurs

Jacob Andring (J)

Department of Biochemistry and Molecular Biology, College of Medicine, University of Florida, Gainesville, FL 32610, USA.
ORCID: 0000-0002-6632-6391

Jacob Combs (J)

Department of Biochemistry and Molecular Biology, College of Medicine, University of Florida, Gainesville, FL 32610, USA.
ORCID: 0000-0001-5657-4773

Robert McKenna (R)

Department of Biochemistry and Molecular Biology, College of Medicine, University of Florida, Gainesville, FL 32610, USA.
ORCID: 0000-0002-2792-935X

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Classifications MeSH

questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Hydrocarbures cycliques › Hydrocarbures aromatiques › Dérivés du benzène › Phénols › Hydroxybenzoates › Salicylates › Acide acétylsalicylique › Aspirin: A Suicide Inhibitor of Carbonic Anhydrase II.
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Lyases › Carbon-oxygen lyases › Hydro-lyases › Carbonic anhydrases › Carbonic anhydrase II › Aspirin: A Suicide Inhibitor of Carbonic Anhydrase II.
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Conformation moléculaire › Conformation des protéines › Éléments structuraux des protéines › Domaine catalytique › Aspirin: A Suicide Inhibitor of Carbonic Anhydrase II.
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Mécanismes moléculaires de l'action pharmacologique › Antienzymes › Aspirin: A Suicide Inhibitor of Carbonic Anhydrase II.
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Cinétique › Aspirin: A Suicide Inhibitor of Carbonic Anhydrase II.
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles moléculaires › Aspirin: A Suicide Inhibitor of Carbonic Anhydrase II.