Composite Hemostatic Nonwoven Textiles Based on Hyaluronic Acid, Cellulose, and Etamsylate.

cellulose etamsylate hemostasis hyaluronic acid nonwoven textile

Journal

Materials (Basel, Switzerland)
ISSN: 1996-1944
Titre abrégé: Materials (Basel)
Pays: Switzerland
ID NLM: 101555929

Informations de publication

Date de publication:
01 Apr 2020
Historique:
received: 09 03 2020
revised: 26 03 2020
accepted: 28 03 2020
entrez: 5 4 2020
pubmed: 5 4 2020
medline: 5 4 2020
Statut: epublish

Résumé

The achievement of rapid hemostasis represents a long-term trend in hemostatic research. Specifically, composite materials are now the focus of attention, based on the given issues and required properties. In urology, different materials are used to achieve fast and effective hemostasis. Additionally, it is desirable to exert a positive influence on local tissue reaction. In this study, three nonwoven textiles prepared by a wet spinning method and based on a combination of hyaluronic acid with either oxidized cellulose or carboxymethyl cellulose, along with the addition of etamsylate, were introduced and assessed in vivo using the rat partial nephrectomy model. A significantly shorter time to hemostasis in seconds (

Identifiants

pubmed: 32244805
pii: ma13071627
doi: 10.3390/ma13071627
pmc: PMC7178357
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Veterinární a Farmaceutická Univerzita Brno
ID : 322/2016/FaF

Déclaration de conflit d'intérêts

The authors declare no conflicts of interest. The funders had no role in the design of the study, in the collection, analyses, or interpretation of data, in the writing of the manuscript, or in the decision to publish the results.

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Auteurs

Pavel Suchý (P)

Department of Human Pharmacology and Toxicology, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences, 612 42 Brno, Czech Republic.

Alice Paprskářová (A)

Department of Human Pharmacology and Toxicology, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences, 612 42 Brno, Czech Republic.

Marta Chalupová (M)

Department of Human Pharmacology and Toxicology, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences, 612 42 Brno, Czech Republic.

Lucie Marholdová (L)

Contipro a.s., 561 02 Dolní Dobrouč, Czech Republic.

Kristina Nešporová (K)

Contipro a.s., 561 02 Dolní Dobrouč, Czech Republic.

Jarmila Klusáková (J)

Department of Human Pharmacology and Toxicology, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences, 612 42 Brno, Czech Republic.

Gabriela Kuzmínová (G)

Department of Human Pharmacology and Toxicology, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences, 612 42 Brno, Czech Republic.

Michal Hendrych (M)

Department of Physiology, Faculty of Medicine, Masaryk University, 625 00 Brno, Czech Republic.
First Department of Pathology, St. Anne's University Hospital and Faculty of Medicine, Masaryk University, 656 91 Brno, Czech Republic.

Vladimír Velebný (V)

Contipro a.s., 561 02 Dolní Dobrouč, Czech Republic.

Classifications MeSH