Primary Neuroendocrine Neoplasms of the Breast: Case Series and Literature Review.
case series
diagnostics
histology
management
neuroendocrine carcinoma of the breast
review
small cell carcinoma of the breast
Journal
Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829
Informations de publication
Date de publication:
20 Mar 2020
20 Mar 2020
Historique:
received:
28
01
2020
revised:
28
02
2020
accepted:
16
03
2020
entrez:
5
4
2020
pubmed:
5
4
2020
medline:
5
4
2020
Statut:
epublish
Résumé
Primary neuroendocrine carcinoma of the breast (NECB) as defined by the World Health Organization (WHO) in 2012 is a rare, but possibly under-diagnosed entity. It is heterogeneous as it entails a wide spectrum of diseases comprising both well-differentiated neuroendocrine tumors of the breast as well as highly aggressive small cell carcinomas. Retrospective screening of hospital charts of 612 patients (2008-2019) from our specialized outpatient unit for neuroendocrine neoplasia revealed five patients diagnosed with NECB. Given the low prevalence of these malignancies, correct diagnosis remains a challenge that requires an interdisciplinary approach. Specifically, NECB may be misclassified as carcinoma of the breast with neuroendocrine differentiation, carcinomas of the breast of no special type/invasive ductal carcinoma, or a metastasis to the breast. Therefore, this study presents multifaceted characteristics as well as the clinical course of these patients and discusses the five cases from our institution in the context of available literature.
Identifiants
pubmed: 32244940
pii: cancers12030733
doi: 10.3390/cancers12030733
pmc: PMC7140078
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Références
Histopathology. 2011 Oct;59(4):619-30
pubmed: 22014043
Clin Imaging. 2014 Sep-Oct;38(5):734-8
pubmed: 25052497
Eur J Cancer. 2013 Jul;49(11):2565-78
pubmed: 23541566
World J Surg. 2005 Jan;29(1):92-101
pubmed: 15599742
Breast J. 2019 May;25(3):519-520
pubmed: 31001910
Chin J Cancer. 2017 May 11;36(1):45
pubmed: 28490384
BMC Cancer. 2014 Mar 04;14:147
pubmed: 24589259
Mod Pathol. 2013 Oct;26(10):1365-70
pubmed: 23599157
Radiat Med. 2008 Jan;26(1):28-32
pubmed: 18236131
Oncol Res Treat. 2014;37(5):266-76
pubmed: 24853787
Case Rep Pathol. 2016;2016:6762085
pubmed: 27840759
Head Neck. 2015 May;37(5):707-15
pubmed: 24596175
Histopathology. 2002 Mar;40(3):211-4
pubmed: 11895485
Oncologist. 2016 Jan;21(1):28-32
pubmed: 26659223
Am J Clin Oncol. 1996 Jun;19(3):322-3
pubmed: 8638551
Breast Care (Basel). 2012 Oct;7(5):408-10
pubmed: 24647781
N Engl J Med. 2011 Feb 10;364(6):501-13
pubmed: 21306237
Eur J Endocrinol. 2015 Jan;172(1):R1-8
pubmed: 25117465
Mod Pathol. 2016 Aug;29(8):788-98
pubmed: 27125358
J Clin Oncol. 2008 May 1;26(13):2124-30
pubmed: 18445841
Semin Diagn Pathol. 2010 Feb;27(1):69-76
pubmed: 20306832
J Clin Oncol. 2006 Jun 20;24(18):2694-6
pubmed: 16702578
Frankf Z Pathol. 1963 Oct 3;73:24-39
pubmed: 14097474
Breast Cancer Res Treat. 2010 Nov;124(2):413-7
pubmed: 20872069
Anticancer Res. 2016 Mar;36(3):921-4
pubmed: 26976979
Cancer. 1992 Nov 1;70(9):2268-77
pubmed: 1356613
Am J Surg Pathol. 2000 Sep;24(9):1231-8
pubmed: 10976697
Korean J Radiol. 2013 May-Jun;14(3):395-9
pubmed: 23690703
Eur Radiol. 2003 Apr;13(4):788-93
pubmed: 12664118
J Infect Dis. 2005 Jan 15;191(2):289-98
pubmed: 15609240
World J Surg Oncol. 2013 Jun 05;11:128
pubmed: 23734899
Breast Cancer. 2007;14(2):250-3
pubmed: 17485914
Pathol Int. 2011 Jan;61(1):49-51
pubmed: 21166944
Cell. 2006 Dec 1;127(5):1041-55
pubmed: 17129787
Neuroendocrinology. 2011;93(4):249-58
pubmed: 21487213
Am J Surg Pathol. 2014 Jan;38(1):13-22
pubmed: 24145643
Breast. 2012 Oct;21(5):652-6
pubmed: 22397895
N Engl J Med. 2017 Jan 12;376(2):125-135
pubmed: 28076709
Am J Pathol. 1993 Dec;143(6):1731-42
pubmed: 8256859
Breast Care (Basel). 2013 May;8(2):149-54
pubmed: 24415964
Case Rep Med. 2017;2017:4812453
pubmed: 28115940
PET Clin. 2014 Jul;9(3):323-9
pubmed: 25030395
Oncol Rep. 2008 Dec;20(6):1369-74
pubmed: 19020716
Oncol Lett. 2011 Sep 1;2(5):887-890
pubmed: 22866145
N Engl J Med. 2014 Jul 17;371(3):224-33
pubmed: 25014687
Ann Surg Oncol. 1998 Apr-May;5(3):261-4
pubmed: 9607629
Cancer. 2008 Nov 15;113(10):2655-64
pubmed: 18853416
Front Med. 2015 Mar;9(1):112-6
pubmed: 25098433
Biomed Res Int. 2014;2014:408459
pubmed: 24701575
Pathologe. 2015 May;36(3):261-70
pubmed: 25986886
J Clin Oncol. 2009 Oct 1;27(28):4656-63
pubmed: 19704057
Ann Oncol. 2004;15 Suppl 4:iv293-8
pubmed: 15477324
Cancer. 2010 Oct 1;116(19):4463-73
pubmed: 20572042