How we treat patients with lung cancer during the SARS-CoV-2 pandemic:


Journal

ESMO open
ISSN: 2059-7029
Titre abrégé: ESMO Open
Pays: England
ID NLM: 101690685

Informations de publication

Date de publication:
04 2020
Historique:
received: 27 03 2020
accepted: 27 03 2020
entrez: 5 4 2020
pubmed: 5 4 2020
medline: 11 4 2020
Statut: ppublish

Résumé

New cases of the novel coronavirus, also known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continue to rise worldwide. A few reports have showed that mortality due to SARS-CoV-2 is higher in elderly patients and other active comorbidities including cancer. To date, no effective treatment has been identified and management for critically ill patients relies on management in intensive care units. Patients with lung cancer are at risk of pulmonary complications from COVID-19. Furthermore, the use of chemotherapy might have a negative impact in patient's outcome. Therefore, the risk/benefit ratio of systemic anticancer treatment (SACT) has to be considered. For each patient, several factors including age and comorbidities, as well as the number of hospital visits for treatment, can influence this risk. Each hospital around the world has issued some internal policy guidelines for oncologists, aiming to limit risks during this difficult time. We hereby propose a tool to support oncologists and physicians in treatment decision for patients with lung cancer. There are several variables to consider, including the extent of the epidemic, the local healthcare structure capacity, the risk of infection to the individual, the status of cancer, patients' comorbidities, age and details of the treatment. Given this heterogeneity, we have based our suggestions bearing in mind some general factors There is not easy, universal solution to oncological care during this crisis and, to complicate matters, the duration of this pandemic is hard to predict. It is important to weigh the impact of each of our decisions in these trying times rather than rely on routine automatisms.

Identifiants

pubmed: 32245904
pii: S2059-7029(20)32621-1
doi: 10.1136/esmoopen-2020-000765
pmc: PMC7211064
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

e000765

Commentaires et corrections

Type : CommentIn
Type : CommentIn

Informations de copyright

© Author (s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. Published by BMJ on behalf of the European Society for Medical Oncology.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Références

N Engl J Med. 2020 Apr 30;382(18):1708-1720
pubmed: 32109013
Lancet. 2020 Mar 21;395(10228):931-934
pubmed: 32164834
Lancet Infect Dis. 2020 Jul;20(7):773
pubmed: 32171390
Lancet Oncol. 2020 Mar;21(3):335-337
pubmed: 32066541
Signal Transduct Target Ther. 2020 Feb 21;5(1):18
pubmed: 32296012
Lancet Respir Med. 2020 May;8(5):475-481
pubmed: 32105632

Auteurs

Giuseppe Banna (G)

Oncology, Ospedale Cannizzaro, Catania, Italy.

Alessandra Curioni-Fontecedro (A)

Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland.

Alex Friedlaender (A)

Department of Oncology, University Hospital of Geneva, Geneva, Switzerland.

Alfredo Addeo (A)

Department of Oncology, University Hospital of Geneva, Geneva, Switzerland. Electronic address: alfredo.addeo@hcuge.ch.

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Classifications MeSH