Vitamin D supplementation reduces the occurrence of colorectal polyps in high-latitude locations.
Cancer prevention
Cancer screening
Colorectal cancer
Colorectal polyps
Epidemiology
High-latitude
Nutrition
Public health
Vitamin D
Journal
Preventive medicine
ISSN: 1096-0260
Titre abrégé: Prev Med
Pays: United States
ID NLM: 0322116
Informations de publication
Date de publication:
06 2020
06 2020
Historique:
received:
21
11
2019
revised:
04
03
2020
accepted:
28
03
2020
pubmed:
5
4
2020
medline:
1
5
2021
entrez:
5
4
2020
Statut:
ppublish
Résumé
There is suggestive evidence for the role of vitamin D in the development of colorectal cancer (CRC). Due to high latitudes in Canada, many Canadians are vitamin D deficient throughout winter. In this analysis, we examined the association between vitamin D supplement use and high-risk adenomatous polyps (HRAPs). The study population was drawn from the biorepository at the Forzani & MacPhail Colon Cancer Screening Centre (CCSC) in Calgary. Individuals enrolled between 2013 and 2016 between the age of 50 and 74 years (n = 1409) were included. When examining the association between any supplemental vitamin D use and HRAPs, a protective effect is observed with an OR
Identifiants
pubmed: 32247012
pii: S0091-7435(20)30096-7
doi: 10.1016/j.ypmed.2020.106072
pii:
doi:
Substances chimiques
Vitamin D
1406-16-2
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
106072Subventions
Organisme : CIHR
Pays : Canada
Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.