Enzymes for pharmaceutical and therapeutic applications.
antimicrobials
enzyme
enzyme therapy
fermentation
infectious diseases
Journal
Biotechnology and applied biochemistry
ISSN: 1470-8744
Titre abrégé: Biotechnol Appl Biochem
Pays: United States
ID NLM: 8609465
Informations de publication
Date de publication:
Jul 2020
Jul 2020
Historique:
received:
04
01
2020
pubmed:
6
4
2020
medline:
27
5
2021
entrez:
6
4
2020
Statut:
ppublish
Résumé
Enzymes are highly efficient and selective biocatalysts, present in the living beings. They exist in enormous varieties in terms of the types of reactions catalyzed by them for instance oxidation-reduction, group transfers within the molecules or between the molecules, hydrolysis, isomerization, ligation, bond cleavage, and bond formation. Besides, enzyme based catalyses are performed with much higher fidelity, under mild reaction conditions and are highly efficient in terms of number of steps, giving them an edge over their chemical counter parts. The unique characteristics of enzymes makes them highly applicable fora number of chemical transformation reactions in pharmaceutical industries, such as group protection and deprotection, selective acylation and deacylation, selective hydrolysis, deracemization, kinetic resolution of racemic mixtures, esterification, transesterification, and many others. In this review, an overview of the enzymes, their production and their applications in pharmaceutical syntheses and enzyme therapies are presented with diagrams, reaction schemes and table for easy understanding of the readers.
Substances chimiques
Enzymes
0
Pharmaceutical Preparations
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
586-601Informations de copyright
© 2020 The Authors. Biotechnology and Applied Biochemistry published by Wiley Periodicals, Inc. on behalf of International Union of Biochemistry and Molecular Biology.
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