INTRARETINAL HYPERREFLECTIVE LINES.
Journal
Retina (Philadelphia, Pa.)
ISSN: 1539-2864
Titre abrégé: Retina
Pays: United States
ID NLM: 8309919
Informations de publication
Date de publication:
01 Jan 2021
01 Jan 2021
Historique:
pubmed:
7
4
2020
medline:
15
9
2021
entrez:
7
4
2020
Statut:
ppublish
Résumé
To report intraretinal hyperreflective lines related to various macular conditions. All cases were imaged with color photographs, autofluorescence images, and spectral-domain optical coherence tomography, some with fluorescein and/or indocyanine green angiography. Demographic data, imaging, course and outcome were retrospectively analyzed. Forty-nine eyes of 43 patients (16 men and 27 women) were included. Hyperreflective vertical lines (38 eyes) or curvilinear lines along the Henle fiber layer (11 eyes) were present in association with various macular conditions: adult vitelliform dystrophy or pattern dystrophy (24 eyes) frequently associated with an epiretinal membrane (six eyes) and/or thick choroid (nine eyes), age-related maculopathy or macular degeneration (nine eyes), partial resorption of subretinal or intraretinal hemorrhages (five eyes), idiopathic macular microhole (two eyes), vitreomacular traction (three eyes), multiple evanescent white dot syndrome (three eyes), fundus flavimaculatus (two eyes), and pachychoroid pigment epitheliopathy (one eye). The lines fully vanished in cases of hemorrhages, multiple evanescent white dot syndrome or resolution of vitreomacular traction, but usually persisted with gradual thinning in the other conditions. The present series showed that intraretinal hyperreflective lines could occur in various inflammatory, degenerative, or tractional conditions. They could reflect a previously unrecognized reaction to various photoreceptor, Müller cell, and/or retinal pigment epithelium damage.
Identifiants
pubmed: 32251237
pii: 00006982-202101000-00010
doi: 10.1097/IAE.0000000000002806
doi:
Types de publication
Journal Article
Multicenter Study
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
82-92Commentaires et corrections
Type : CommentIn
Type : CommentIn
Type : CommentIn
Type : CommentIn
Références
Gass JD. A clinicopathologic study of a peculiar foveomaculardystrophy. Trans Am Ophthalmol Soc 1974;72:139–156.
Freund KB, Laud K, Lima LH, et al. Acquired vitelliform lesions: correlation of clinical findings and multiple imaging analyses. Retina 2011;31:13–25.
Chen KC, Jung JJ, Curcio CA, et al. Intraretinal hyperreflective foci in acquired vitelliform lesions of the macula: clinical and histologic study. Am J Ophthalmol 2016;164:89–98.
Syrbe S, Kuhrt H, Gärtner U, et al. Müller glial cells of the primate foveola: an electron microscopical study. Exp Eye Res 2018;167:110–117.
Lima LH, Laud K, Freund KB, et al. Acquired vitelliform lesion associated with large drusen. Retina 2012;32:647–651.
Balaratnasingam C, Yannuzzi LA, Curcio CA, et al. Associations between retinal pigment epithelium and drusen volume changes during the lifecycle of large drusenoid pigment epithelial detachments. Invest Ophthalmol Vis Sci 2016;57:5479–5489.
Finger RP, Charbel Issa P, Kellner U, et al. Spectral domain optical coherence tomography in adult-onset vitelliform macular dystrophy with cuticular drusen. Retina 2010;30:1455–1464.
Mrejen-Uretsky S, Ayrault S, Nghiem-Buffet S, et al. Choroidal thickening in patients with cuticular drusen combined with vitelliform macular detachment. Retina 2016;36:1111–1118.
Ikeda T, Sato K, Danjo Y, et al. Central serous chorioretinopathy exhibiting a vitelliform lesion similar to best disease. Arch Ophthalmol 2003;121:146–147.
Giuffrè C, Miserocchi E, Modorati G, et al. Central serous chorioretinopathylike mimicking multifocal vitelliform macular dystrophy: an ocular side effect of mitogen/extracellular signal-regulated kinase inhibitors. Retin Cases Brief Rep 2018;12:172–176.
Dupas B, Tadayoni R, Erginay A, et al. Subfoveal deposits secondary to idiopathic epiretinal membranes. Ophthalmology 2009;116:1794–1798.
Chowers I, Tiosano L, Audo I, et al. Adult-onset foveomacular vitelliform dystrophy: a fresh perspective. Prog Retin Eye Res 2015;47:64–85.
Pison A, Dupas B, Couturier A, et al. Evolution of subfoveal detachments secondary to idiopathic epiretinal membranes after surgery. Ophthalmology 2016;123:583–589.
Gonzales CR, Lin AP, Engstrom RE, Kreiger AE. Bilateral vitelliform maculopathy and deferoxamine toxicity. Retina 2004;24:464–467.
Ozkaya A, Garip R, Nur Tarakcioglu H, et al. Clinical and imaging findings of pattern dystrophy subtypes; diagnostic errors and unnecessary treatment in clinical practice. J Fr Ophtalmol 2018;41:21–29.
Cheung CMG, Gan A, Yanagi Y, et al. Association between choroidal thickness and drusen subtypes in age-related macular degeneration. Ophthalmol Retina 2018;2:1196–1205.
Coscas F, Puche N, Coscas G, et al. Comparison of macular choroidal thickness in adult onset foveomacular vitelliform dystrophy and age-related macular degeneration. Invest Ophthalmol Vis Sci 2014;55:64–69.
Warrow DJ, Hoang QV, Freund KB. Pachychoroid pigment epitheliopathy. Retina 2013;33:1659–1672.
Asai T, Ikuno Y, Nishida K. Macular microstructures and prognostic factors in myopic subretinal hemorrhages. Invest Ophthalmol Vis Sci 2014;55:226–232.
Au A, Hou K, Baumal CR, Sarraf D. Radial hemorrhage in henle layer in macular telangiectasia Type 2. JAMA Ophthalmol 2018;136:1182–1185.
Tatlipinar S, Shah SM, Nguyen QD. Optical coherence tomography features of sub-internal limiting membrane hemorrhage and preretinal membrane in Valsalva retinopathy. Can J Ophthalmol 2007;42:129–130.
Gal-Or O, Priel E, Rosenblatt I, et al. Multimodal imaging in an unusual cluster of multiple evanescent white dot syndrome. J Ophthalmol 2017;2017:7535320.
Chen KC, Marsiglia M, Dolz-Marco R, et al. Foveal exudate and choroidal neovascularization in atypical cases of multiple evanescent white dot syndrome. Retina 2017;37:2025–2034.
Gal-Or O, Sorenson JA, Gattoussi S, et al. Multiple evanescent white dot syndrome with subretinal deposits. Retin Cases Brief Rep 2019;13:314–319.
Gaudric A, Mrejen S. Why the dots are black only in the late phase of the indocyanine green angiography in multiple evanescent white dot syndrome. Retin Cases Brief Rep 2017;11:S81–S85.
Govetto A, Bhavsar KV, Virgili G, et al. Tractional abnormalities of the central foveal bouquet in epiretinal membranes: clinical spectrum and pathophysiological perspectives. Am J Ophthalmol 2017;184:167–180.
Cairns JD, McCombe MF. Microholes of the fovea centralis. Aust NZ J Ophthalmol 1988;16:75–79.
Reddy CV, Folk JC, Feist RM. Microholes of the macula. Arch Ophthalmol 1996;114:413–416.
Douglas RS, Duncan J, Brucker A, et al. Foveal spot: a report of thirteen patients. Retina 2003;23:348–353.
Zambarakji HJ, Schlottmann P, Tanner V, et al. Macular microholes: pathogenesis and natural history. Br J Ophthalmol 2005;89:189–193.
Gella L, Raman R, Pal SS, et al. Morphological and functional changes in spectral domain optical coherence tomography and microperimetry in macular microhole variants: spectral domain optical coherence tomography and microperimetry correlation. Indian J Ophthalmol 2012;60:53–56.
Dansingani KK, Tan ACS, Gilani F, et al. Subretinal hyperreflective material imaged with optical coherence tomography angiography. Am J Ophthalmol 2016;169:235–248.
Paques M, Rossant F, Finocchio L, et al. Attenuation outer retinal bands on optical coherence tomography following macular edema: a possible manifestation of photoreceptor misalignment. Retina 2020 Jan 7. doi: 10.1097/IAE.0000000000002738. [Epub ahead of print]
doi: 10.1097/IAE.0000000000002738