Total Synthesis and Antitrypanosomal Activity of Janadolide and Simplified Analogues.

Antiprotozoal Agents / chemical synthesis Molecular Structure Parasitic Sensitivity Tests Peptides, Cyclic / chemical synthesis Trypanosoma brucei rhodesiense / drug effects Trypanosoma cruzi / drug effects

Journal

Organic letters
ISSN: 1523-7052
Titre abrégé: Org Lett
Pays: United States
ID NLM: 100890393

Informations de publication

Date de publication:
17 04 2020
Historique:
pubmed: 7 4 2020
medline: 30 6 2021
entrez: 7 4 2020
Statut: ppublish

Résumé

Janadolide is a cyclic depsipeptide natural product isolated from the marine cyanobacterium

Identifiants

DOI: 10.1021/acs.orglett.0c00840 PMID: 32251602
pubmed: 32251602
doi: 10.1021/acs.orglett.0c00840
doi:

Substances chimiques

Antiprotozoal Agents 0
Peptides, Cyclic 0
janadolide 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

3089-3093

Auteurs

Jonathan H Chung (JH)

School of Chemistry, The University of Sydney, Sydney, New South Wales 2006, Australia.

Arthur H Tang (AH)

School of Chemistry, The University of Sydney, Sydney, New South Wales 2006, Australia.

Kieran Geraghty (K)

School of Chemistry, The University of Sydney, Sydney, New South Wales 2006, Australia.

Leo Corcilius (L)

School of Chemistry, The University of Sydney, Sydney, New South Wales 2006, Australia.

Marcel Kaiser (M)

Swiss Tropical and Public Health Institute, Socinstrasse 57, 4051 Basel, Switzerland.
University of Basel, 4001 Basel, Switzerland.

Richard J Payne (RJ)

School of Chemistry, The University of Sydney, Sydney, New South Wales 2006, Australia.
ORCID: 0000-0002-3618-9226

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antiparasitaires › Antiprotozoaires › Total Synthesis and Antitrypanosomal Activity...
questionsmedicales.fr › Phénomènes chimiques › Structure moléculaire › Total Synthesis and Antitrypanosomal Activity...
questionsmedicales.fr › Techniques d'investigation › Évaluation préclinique de médicament › Tests de sensibilité parasitaire › Total Synthesis and Antitrypanosomal Activity...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Peptides cycliques › Total Synthesis and Antitrypanosomal Activity...
questionsmedicales.fr › Eucaryotes › Euglénozoaires › Kinetoplastida › Trypanosomatina › Trypanosoma › Trypanosoma brucei rhodesiense › Total Synthesis and Antitrypanosomal Activity...
questionsmedicales.fr › Eucaryotes › Euglénozoaires › Kinetoplastida › Trypanosomatina › Trypanosoma › Trypanosoma cruzi › Total Synthesis and Antitrypanosomal Activity...