In vivo biodistribution of calcium phosphate nanoparticles after intravascular, intramuscular, intratumoral, and soft tissue administration in mice investigated by small animal PET/CT.
Animals
Calcium Phosphates
/ administration & dosage
Cell Line, Tumor
Gallium Radioisotopes
/ administration & dosage
Heterocyclic Compounds, 1-Ring
/ administration & dosage
Humans
Injections, Intramuscular
Mice, Inbred BALB C
Nanoparticles
/ administration & dosage
Neoplasms
/ diagnostic imaging
Positron Emission Tomography Computed Tomography
Biodistribution
Calcium phosphate
Computer tomography
Imaging
Nanoparticles
Positron-emission tomography
Journal
Acta biomaterialia
ISSN: 1878-7568
Titre abrégé: Acta Biomater
Pays: England
ID NLM: 101233144
Informations de publication
Date de publication:
06 2020
06 2020
Historique:
received:
14
02
2020
revised:
13
03
2020
accepted:
24
03
2020
pubmed:
7
4
2020
medline:
16
4
2021
entrez:
7
4
2020
Statut:
ppublish
Résumé
Calcium phosphate nanoparticles were covalently surface-functionalized with the ligand DOTA and loaded with the radioisotope
Identifiants
pubmed: 32251787
pii: S1742-7061(20)30172-0
doi: 10.1016/j.actbio.2020.03.031
pii:
doi:
Substances chimiques
Calcium Phosphates
0
Gallium Radioisotopes
0
Heterocyclic Compounds, 1-Ring
0
1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid
1HTE449DGZ
calcium phosphate
97Z1WI3NDX
Gallium-68
98B30EPP5S
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
244-253Informations de copyright
Copyright © 2020. Published by Elsevier Ltd.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.