Endoscopic negative pressure therapy with open-pore film drainage and open-pore polyurethane sponge drainage for iatrogenic perforation of the esophagus.


Journal

Endoscopy
ISSN: 1438-8812
Titre abrégé: Endoscopy
Pays: Germany
ID NLM: 0215166

Informations de publication

Date de publication:
05 2020
Historique:
pubmed: 7 4 2020
medline: 16 2 2021
entrez: 7 4 2020
Statut: ppublish

Résumé

Management of iatrogenic esophageal perforation (IEP) is challenging. Endoscopic negative pressure therapy (ENPT) is an emerging and effective tool for the treatment of gastrointestinal and anastomotic leaks. We have used ENPT as first-line therapy for IEP since 2017. The aim of this study was to present our results with this strategy in patients with IEP. Nine patients were treated with ENPT for IEP between August 2017 and August 2019. Their treatment characteristics, including duration of therapy, strategy used, and outcomes, were analyzed. Treatment included ENPT with open-pore film drainage (OFD) and open-pore polyurethane foam drainage (OPD). Early diagnosis (< 24 hours) of IEP occurred in four patients. After a mean (standard deviation) of 19.0 (13.5) days of ENPT, 6.4 (3.4) endoscopies, and 38.1 (40.3) days of hospitalization, endoscopic treatment was effective and successful in all of the patients. Additional video-assisted thoracic surgery (VATS) was done in four patients. ENPT is an effective new method for the management of IEP. ENPT with OFD and OPD can be combined with minimally invasive operative methods for sepsis control in IEP.

Sections du résumé

BACKGROUND
Management of iatrogenic esophageal perforation (IEP) is challenging. Endoscopic negative pressure therapy (ENPT) is an emerging and effective tool for the treatment of gastrointestinal and anastomotic leaks. We have used ENPT as first-line therapy for IEP since 2017. The aim of this study was to present our results with this strategy in patients with IEP.
METHODS
Nine patients were treated with ENPT for IEP between August 2017 and August 2019. Their treatment characteristics, including duration of therapy, strategy used, and outcomes, were analyzed. Treatment included ENPT with open-pore film drainage (OFD) and open-pore polyurethane foam drainage (OPD).
RESULTS
Early diagnosis (< 24 hours) of IEP occurred in four patients. After a mean (standard deviation) of 19.0 (13.5) days of ENPT, 6.4 (3.4) endoscopies, and 38.1 (40.3) days of hospitalization, endoscopic treatment was effective and successful in all of the patients. Additional video-assisted thoracic surgery (VATS) was done in four patients.
CONCLUSIONS
ENPT is an effective new method for the management of IEP. ENPT with OFD and OPD can be combined with minimally invasive operative methods for sepsis control in IEP.

Identifiants

pubmed: 32252093
doi: 10.1055/a-1139-0772
doi:

Substances chimiques

Polyurethanes 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

377-382

Commentaires et corrections

Type : ErratumIn
Type : CommentIn

Informations de copyright

© Georg Thieme Verlag KG Stuttgart · New York.

Déclaration de conflit d'intérêts

The authors declare that they have no conflict of interest.

Auteurs

Dörte Wichmann (D)

Department of General, Visceral and Transplantation Surgery, University Hospital Tübingen, Tübingen, Germany.

Dietmar Stüker (D)

Department of General, Visceral and Transplantation Surgery, University Hospital Tübingen, Tübingen, Germany.

Ulrike Schempf (U)

Department of Gastroenterology, Hepatology, and Infectious Diseases, University Hospital Tübingen, Tübingen, Germany.

Christoph R Werner (CR)

Department of Gastroenterology, Hepatology, and Infectious Diseases, University Hospital Tübingen, Tübingen, Germany.

Volker Steger (V)

Department of Thoracic and Cardiovascular Surgery, University Hospital Tübingen, Tübingen, Germany.

Alfred Königsrainer (A)

Department of General, Visceral and Transplantation Surgery, University Hospital Tübingen, Tübingen, Germany.

Ulrich Schweizer (U)

Department of General, Visceral and Transplantation Surgery, University Hospital Tübingen, Tübingen, Germany.

Rami Archid (R)

Department of General, Visceral and Transplantation Surgery, University Hospital Tübingen, Tübingen, Germany.

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