The Association of Psychosocial Factors and Exercise-Induced Hypoalgesia in Healthy People and People With Musculoskeletal Pain: A Systematic Review.
exercise
exercise-induced hypoalgesia
musculoskeletal pain
psychosocial factors
Journal
Pain practice : the official journal of World Institute of Pain
ISSN: 1533-2500
Titre abrégé: Pain Pract
Pays: United States
ID NLM: 101130835
Informations de publication
Date de publication:
07 2020
07 2020
Historique:
received:
02
12
2019
revised:
20
03
2020
accepted:
26
03
2020
pubmed:
8
4
2020
medline:
24
11
2020
entrez:
8
4
2020
Statut:
ppublish
Résumé
Exercise, a cornerstone in current treatments for people with musculoskeletal pain, elicits a phenomenon called exercise-induced hypoalgesia (EIH), which may result in reduced pain intensity and/or increased pain thresholds. However, EIH can be impaired in patients with musculoskeletal pain, and psychosocial factors may play a mediating role in EIH. The aim of this study was to systematically review the scientific literature regarding the association between psychosocial factors and EIH in healthy people and people with musculoskeletal pain. An extensive search in databases including Medline Ovid, Embase, Web of Science, PsycINFO Ovid, and the Cumulative Index to Nursing and Allied Health Literature (CINAHL) EBSCOhost was carried out. Two reviewers independently carried out study selection, data extraction, and critical appraisal. Included studies analyzed the association or effect of psychosocial factors on EIH in adults with or without musculoskeletal pain. Nine cross-sectional studies were included, 6 involving healthy people and 4 involving people with musculoskeletal pain; 1 study included both. Overall risk of bias was high. Different types of exercise bouts, psychosocial factors, and/or outcome measures were used across studies. In healthy people and people with musculoskeletal pain, most studies did not find an association between psychosocial factors and EIH. However, 1 study involving musculoskeletal pain and 2 studies with healthy people did find a significant association. Due to poor quality and heterogeneity between studies, no conclusions can be drawn regarding whether psychosocial factors are associated with EIH or not. This review includes recommendations and directions for further research to investigate the role of psychosocial factors on EIH.
Sections du résumé
BACKGROUND
Exercise, a cornerstone in current treatments for people with musculoskeletal pain, elicits a phenomenon called exercise-induced hypoalgesia (EIH), which may result in reduced pain intensity and/or increased pain thresholds. However, EIH can be impaired in patients with musculoskeletal pain, and psychosocial factors may play a mediating role in EIH.
OBJECTIVE
The aim of this study was to systematically review the scientific literature regarding the association between psychosocial factors and EIH in healthy people and people with musculoskeletal pain.
METHODS
An extensive search in databases including Medline Ovid, Embase, Web of Science, PsycINFO Ovid, and the Cumulative Index to Nursing and Allied Health Literature (CINAHL) EBSCOhost was carried out. Two reviewers independently carried out study selection, data extraction, and critical appraisal. Included studies analyzed the association or effect of psychosocial factors on EIH in adults with or without musculoskeletal pain.
RESULTS
Nine cross-sectional studies were included, 6 involving healthy people and 4 involving people with musculoskeletal pain; 1 study included both. Overall risk of bias was high. Different types of exercise bouts, psychosocial factors, and/or outcome measures were used across studies. In healthy people and people with musculoskeletal pain, most studies did not find an association between psychosocial factors and EIH. However, 1 study involving musculoskeletal pain and 2 studies with healthy people did find a significant association.
CONCLUSION
Due to poor quality and heterogeneity between studies, no conclusions can be drawn regarding whether psychosocial factors are associated with EIH or not. This review includes recommendations and directions for further research to investigate the role of psychosocial factors on EIH.
Types de publication
Journal Article
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
676-694Informations de copyright
© 2020 World Institute of Pain.
Références
Breivik H, Eisenberg E, O’Brien T. The individual and societal burden of chronic pain in Europe: the case for strategic prioritisation and action to improve knowledge and availability of appropriate care. BMC Public Health. 2013;13:1229.
Gaskin DJ, Richard P. The economic costs of pain in the United States. J Pain. 2012;13:715-724.
Andersen LL, Christensen KB, Holtermann A, et al. Effect of physical exercise interventions on musculoskeletal pain in all body regions among office workers: a one-year randomized controlled trial. Man Ther. 2010;15:100-104.
van Tulder MW, Koes BW, Bouter LM. Conservative treatment of acute and chronic nonspecific low back pain: a systematic review of randomized controlled trials of the most common interventions. Spine. 1997;22:2128-2156.
Booth J, Moseley GL, Schiltenwolf M, Cashin A, Davies M, Hübscher M. Exercise for chronic musculoskeletal pain: a biopsychosocial approach. Musculoskeletal Care. 2017;15:413-421.
O'Connor PJ, Cook DB. Exercise and pain: the neurobiology, measurement, and laboratory study of pain in relation to exercise in humans. Exerc Sport Sci Rev. 1999;27:119-166.
Naugle KM, Fillingim RB, Riley JL 3rd. A meta-analytic review of the hypoalgesic effects of exercise. J Pain. 2012;13:1139-1150.
Jones MD, Valenzuela T, Booth J, Taylor JL, Barry BK. Explicit education about exercise-induced hypoalgesia influences pain responses to acute exercise in healthy adults: a randomized controlled trial. J Pain. 2017;18:1409-1416.
Koltyn KF. Analgesia following exercise: a review. Sports Med. 2000;29:85-98.
Rice D, Nijs J, Kosek E, et al. Exercise-induced hypoalgesia in pain-free and chronic pain populations: state of the art and future directions. J Pain. 2019;20:1249-1266.
Staud R, Robinson ME, Price DD. Isometric exercise has opposite effects on central pain mechanisms in fibromyalgia patients compared to normal controls. Pain. 2005;118:176-184.
Lannersten L, Kosek E. Dysfunction of endogenous pain inhibition during exercise with painful muscles in patients with shoulder myalgia and fibromyalgia. Pain. 2010;151:77-86.
Kosek E, Lundberg L. Segmental and plurisegmental modulation of pressure pain thresholds during static muscle contractions in healthy individuals. Eur J Pain. 2003;7:251-258.
Naugle KM, Naugle KE, Fillingim RB, Samuels B, Riley JL III. Intensity thresholds for aerobic exercise-induced hypoalgesia. Med Sci Sports Exerc. 2014;46:817.
Bement MKH, Rasiarmos RL, DiCapo JM, et al. The role of the menstrual cycle phase in pain perception before and after an isometric fatiguing contraction. Eur J Appl Physiol. 2009;106:105-112.
Larivière M, Goffaux P, Marchand S, Julien N. Changes in pain perception and descending inhibitory controls start at middle age in healthy adults. Clin J Pain. 2007;23:506-510.
Lautenbacher S, Peters JH, Heesen M, Scheel J, Kunz M. Age changes in pain perception: a systematic-review and meta-analysis of age effects on pain and tolerance thresholds. Neurosci Biobehav Rev. 2017;75:104-113.
Naugle KM, Naugle KE, Riley JL III. Reduced modulation of pain in older adults after isometric and aerobic exercise. J Pain. 2016;17:719-728.
Wiesenfeld-Hallin Z. Sex differences in pain perception. Gend Med. 2005;2:137-145.
Ickmans K, Malfliet A, De Kooning M, et al. Lack of gender and age differences in pain measurements following exercise in people with chronic whiplash-associated disorders. Pain Physician. 2017;20:E829-E840.
Vaegter HB, Handberg G, Graven-Nielsen T. Hypoalgesia after exercise and the cold pressor test is reduced in chronic musculoskeletal pain patients with high pain sensitivity. Clin J Pain. 2016;32:58-69.
Van Oosterwijck J, Nijs J, Meeus M, et al. Pain inhibition and postexertional malaise in myalgic encephalomyelitis/chronic fatigue syndrome: an experimental study. J Intern Med. 2010;268:265-278.
Fridén C, Thoors U, Glenmark B, et al. Higher pain sensitivity and lower muscle strength in postmenonpausal women with early rheumatoid arthritis compared with age-matched healthy women-a pilot study. Disabil Rehabil. 2013;35:1350-1356.
Löfgren M, Opava CH, Demmelmaier I, et al. Pain sensitivity at rest and during muscle contraction in persons with rheumatoid arthritis: a substudy within the Physical Activity in Rheumatoid Arthritis 2010 study. Arthritis Res Ther. 2018;20:48.
Meeus M, Roussel NA, Truijen S, Nijs J. Reduced pressure pain thresholds in response to exercise in chronic fatigue syndrome but not in chronic low back pain: an experimental study. J Rehabil Med. 2010;42:884-890.
Smith A, Ritchie C, Pedler A, McCamley K, Roberts K, Sterling M. Exercise induced hypoalgesia is elicited by isometric, but not aerobic exercise in individuals with chronic whiplash associated disorders. Scand J Pain. 2017;15:14-21.
Kehlet H, Jensen TS, Woolf CJ. Persistent postsurgical pain: risk factors and prevention. Lancet. 2006;367:1618-1625.
van Wijk G, Veldhuijzen DS. Perspective on diffuse noxious inhibitory controls as a model of endogenous pain modulation in clinical pain syndromes. J Pain. 2010;11:408-419.
Linton SJ, Shaw WS. Impact of psychological factors in the experience of pain. Phys Ther. 2011;91:700-711.
Gatchel RJ, Polatin PB, Mayer TG. The dominant role of psychosocial risk factors in the development of chronic low back pain disability. Spine. 1995;20:2702-2709.
Merlijn VP, Hunfeld JA, van der Wouden JC, Hazebroek-Kampschreur AA, Koes BW, Passchier J. Psychosocial factors associated with chronic pain in adolescents. Pain. 2003;101:33-43.
Tang J, Gibson SJ. A psychophysical evaluation of the relationship between trait anxiety, pain perception, and induced state anxiety. J Pain. 2005;6:612-619.
Weissman-Fogel I, Sprecher E, Pud D. Effects of catastrophizing on pain perception and pain modulation. Exp Brain Res. 2008;186:79-85.
Brett KE, Bennett A, Ritchie LJ, Knoll GA. Physical frailty and functional status in patients with advanced kidney disease: a protocol for a systematic review. Syst Rev. 2017;6:133.
Bishop MD, Horn ME, George SZ. Exercise-induced pain intensity predicted by pre-exercise fear of pain and pain sensitivity. Clin J Pain. 2011;27:398-404.
George SZ, Dover GC, Wallace MR, et al. Biopsychosocial influence on exercise-induced delayed onset muscle soreness at the shoulder: pain catastrophizing and catechol-o-methyltransferase (COMT) diplotype predict pain ratings. Clin J Pain. 2008;24:793-801.
Cook DB, Stegner AJ, Ellingson LD. Exercise alters pain sensitivity in Gulf War veterans with chronic musculoskeletal pain. J Pain. 2010;11:764-772.
Geva N, Pruessner J, Defrin R. Triathletes lose their advantageous pain modulation under acute psychosocial stress. Med Sci Sports Exerc. 2017;49:333-341.
Nijs J, Van de Putte K, Louckx F, Truijen S, De Meirleir K. Exercise performance and chronic pain in chronic fatigue syndrome: the role of pain catastrophizing. Pain Med. 2008;9:1164-1172.
Gliottoni RC, Motl RW. Effect of caffeine on leg-muscle pain during intense cycling exercise: possible role of anxiety sensitivity. Int J Sport Nutr Exerc Metab. 2008;18:103-115.
Gülşen Ç, Güçlü Gündüz A, Söke F, Çekim K, Aydin Y, Akçali D. The effects of kinesiophobia on pain, fatigue severity, functional exercise capacity, functional status and quality of life in fibromyalgia. Ann Rheum Dis. 2018;77:1835.
Hennings A, Schwarz MJ, Riemer S, Stapf TM, Selberdinger VB, Rief W. The influence of physical activity on pain thresholds in patients with depression and multiple somatoform symptoms. Clin J Pain. 2012;28:782-789.
Koltyn KF, Arbogast RW. Perception of pain after resistance exercise. Br J Sports Med. 1998;32:20-24.
Koltyn KF, Garvin AW, Gardiner RL, Nelson TF. Perception of pain following aerobic exercise. Med Sci Sports Exerc. 1996;28:1418-1421.
Coombes BK, Wiebusch M, Heales L, Stephenson A, Vicenzino B. Isometric exercise above but not below an individual's pain threshold influences pain perception in people with lateral epicondylalgia. Clin J Pain. 2016;32:1069-1075.
Stults-Kolehmainen MA, Lu T, Ciccolo JT, Bartholomew JB, Brotnow L, Sinha R. Higher chronic psychological stress is associated with blunted affective responses to strenuous resistance exercise: RPE, pleasure, pain. Psychol Sport Exerc. 2016;22:27-36.
Mora Solis FR. Physical activity and its association with pain-related distress and pain processing before and after exercise-induced low back pain. Dissertation Abstracts International: Section B: The Sciences and Engineering. 2018;79(1-B(E)).
Bement MKH, Weyer A, Hartley S, Drewek B, Harkins AL, Hunter SK. Pain perception after isometric exercise in women with fibromyalgia. Arch Phys Med Rehabil. 2011;92:89-95.
Brellenthin AG, Crombie KM, Cook DB, Sehgal N, Koltyn KF. Psychosocial influences on exercise-induced hypoalgesia. Pain Med. 2017;18:538-550.
Lemley KJ, Hunter SK, Bement MK. Conditioned pain modulation predicts exercise-induced hypoalgesia in healthy adults. Med Sci Sports Exerc. 2015;47:176-184.
Motl RW, O'Connor PJ, Boyd CM, Dishman RK. Low intensity pain reported during elicitation of the H-reflex: no effects of trait anxiety and high intensity cycling exercise. Brain Res. 2002;951:53-58.
Naugle KM, Naugle KE, Fillingim RB, Riley JL 3rd. Isometric exercise as a test of pain modulation: effects of experimental pain test, psychological variables, and sex. Pain Med. 2014;15:692-701.
Ohlman T, Miller L, Naugle KE, Naugle KM. Physical activity levels predict exercise-induced hypoalgesia in older adults. Med Sci Sports Exerc. 2018;50:2101-2109. https://doi.org/10.1249/mss.0000000000001661
Vaegter HB, Madsen AB, Handberg G, Graven-Nielsen T. Kinesiophobia is associated with pain intensity but not pain sensitivity before and after exercise: an explorative analysis. Physiotherapy. 2018;104:187-193.
Lemley KJ. Mechanisms of isometric exercise-induced hypoalgesia in young and older adults. Dissertation Abstracts International: Section B: The Sciences and Engineering. 2015;75(12-B(E)).
Lima LV, Abner TS, Sluka KA. Does exercise increase or decrease pain? Central mechanisms underlying these two phenomena. J Physiol. 2017;595:4141-4150.
O'Neill S, O'Neill L. Improving QST reliability-more raters, tests, or occasions? A multivariate generalizability study. J Pain. 2015;16:454-462.