Disappearance of an anticoagulation-resistant left atrial appendage thrombus after administration of low-dose pimobendan.
Direct oral anticoagulant
Left atrial thrombus
Pimobendan
Transesophageal echocardiography
Journal
Journal of cardiology cases
ISSN: 1878-5409
Titre abrégé: J Cardiol Cases
Pays: Japan
ID NLM: 101549579
Informations de publication
Date de publication:
Apr 2020
Apr 2020
Historique:
received:
24
07
2019
revised:
02
12
2019
accepted:
09
12
2019
entrez:
8
4
2020
pubmed:
8
4
2020
medline:
8
4
2020
Statut:
epublish
Résumé
Anticoagulation therapy is essential for preventing thrombus formation in the left atrial appendage (LAA) and subsequent ischemic strokes in patients with atrial fibrillation (AF). The complete disappearance of any existing LAA thrombi is crucial before AF ablation. Currently, warfarin and direct oral anticoagulants are widely used for this purpose. However, treatment strategies for anticoagulation-resistant LAA thrombi are not well established. Here, we present a case of an 85-year-old male who was scheduled to undergo AF ablation. He developed an LAA thrombus that was resistant to 300 mg/day of dabigatran. Low-dose pimobendan was prescribed in addition to dabigatran; three months later, the thrombus was dissolved successfully. This case demonstrates the potential efficacy of a low-dose oral inotrope for treating an anticoagulation-resistant LAA thrombus. <
Identifiants
pubmed: 32256866
doi: 10.1016/j.jccase.2019.12.007
pii: S1878-5409(19)30128-8
pmc: PMC7125383
doi:
Types de publication
Case Reports
Langues
eng
Pagination
157-160Informations de copyright
© 2019 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.
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