Optic nerve sheath meningioma-findings in the contralateral optic nerve tract: A case report.

functional magnetic resonance imaging ganglion cell complex magnetic resonance imaging optic nerve sheath meningioma retinal nerve fibre layer visual electrophysiology

Journal

Molecular and clinical oncology
ISSN: 2049-9450
Titre abrégé: Mol Clin Oncol
Pays: England
ID NLM: 101613422

Informations de publication

Date de publication:
May 2020
Historique:
received: 22 04 2019
accepted: 24 01 2020
entrez: 8 4 2020
pubmed: 8 4 2020
medline: 8 4 2020
Statut: ppublish

Résumé

The aim of the present study was to observe visual pathway changes on the contralateral side in optic nerve sheath meningioma (ONSM). The authors present a case report of a 43-year-old patient with OfNSM on the right side. A complex ophthalmic examination was performed, including an assessment of visual functions, an electrophysiology examination and functional and structural MRI examinations. Visual acuity of the right eye after ONSM remained with no light perception, while that of the left side was normal. The visual field of the left eye was normal as was colour perception. An electrophysiology examination using a pattern electroretinogram revealed low amplitude values in the right eye. In the left eye, the finding was at the lower limit of normal results. The pattern visual evoked potential exhibited a bilateral lesion with a larger decrease in response after stimulation of the right eye. The structural MRI revealed intraorbital atrophy of the optic nerve on the right side throughout the whole course, which was accompanied by atrophy of the right half of the optic chiasm. Functional magnetic resonance imaging revealed zero activity after stimulation of the right eye and decreased activity in the visual centre after stimulation of the left eye. The present study demonstrated that unilateral damage to the optic nerve in ONSM is accompanied by significant changes on the contralateral side of the optic pathway.

Identifiants

pubmed: 32257196
doi: 10.3892/mco.2020.2012
pii: MCO-0-0-2012
pmc: PMC7087475
doi:

Types de publication

Journal Article

Langues

eng

Pagination

411-414

Informations de copyright

Copyright: © Lestak et al.

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Auteurs

Jan Lestak (J)

JL Clinic, Prague 15800, Czech Republic.
Czech Technical University of Prague, Faculty of Biomedical Engineering, Kladno 27201, Czech Republic.

Pavel Haninec (P)

Department of Neurosurgery, Third Faculty of Medicine, Charles University, Teaching Hospital Královské Vinohrady, Prague 10034, Czech Republic.

Martin Kyncl (M)

JL Clinic, Prague 15800, Czech Republic.
Department of Radiology, Second Medical Faculty Charles University and Motol University Hospital, Prague 15006, Czech Republic.

Jaroslav Tintera (J)

JL Clinic, Prague 15800, Czech Republic.

Classifications MeSH