In Preparation for Outdoor Pharming: Griffithsin Can Be Expressed in
N. excelsiana
antiviral
ensile
griffithsin
microbicide
silage
Journal
Frontiers in bioengineering and biotechnology
ISSN: 2296-4185
Titre abrégé: Front Bioeng Biotechnol
Pays: Switzerland
ID NLM: 101632513
Informations de publication
Date de publication:
2020
2020
Historique:
received:
09
12
2019
accepted:
28
02
2020
entrez:
8
4
2020
pubmed:
8
4
2020
medline:
8
4
2020
Statut:
epublish
Résumé
Griffithsin is an algae-derived lectin with strong anti-viral activity against HIV and a positive safety profile. Multiple clinical studies are investigating griffithsin's utility as topical HIV microbicide. HIV microbicides are an extremely cost-sensitive market and plant-based griffithsin protein expression has the potential to meet those demands. The griffithsin product used in the clinic has been expressed and purified in
Identifiants
pubmed: 32258012
doi: 10.3389/fbioe.2020.00199
pmc: PMC7093594
doi:
Types de publication
Journal Article
Langues
eng
Pagination
199Subventions
Organisme : NIAID NIH HHS
ID : U19 AI113182
Pays : United States
Informations de copyright
Copyright © 2020 Eapen, Cates, Mundell, Palmer and Fuqua.
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