Burden of tuberculosis and challenges related to screening and diagnosis in Ethiopia.
AFB, acid fast bacilli
ANC, ant-natal care
ART, anti-retroviral therapy, DOTS, directly observed treatment, short course
Diagnosis
EPTB, extra pulmonary tuberculosis
Ethiopia
FMoH, Federal Ministry of Health
HIV, human immunodeficiency virus
MDR-TB, multi-drug resistant tuberculosis
Maternal and child health
NGOs, non-governmental organizations
NTB, National TB program
PFSA, Pharmaceutical Fund and Supply Agency
PMTCT, prevention mother to child transmission
PNC, postnatal care
Screening
TB, tuberculosis
Tuberculosis
WHO, World Health Organization
Xpert mtb/rif assay
eHMIS, electronic Health Management Information System
Journal
Journal of clinical tuberculosis and other mycobacterial diseases
ISSN: 2405-5794
Titre abrégé: J Clin Tuberc Other Mycobact Dis
Pays: England
ID NLM: 101682877
Informations de publication
Date de publication:
May 2020
May 2020
Historique:
entrez:
8
4
2020
pubmed:
8
4
2020
medline:
8
4
2020
Statut:
epublish
Résumé
One-third of tuberculosis (TB) cases in Ethiopia are missing from care for reasons that are not well studied. The aim of this study was to assess TB burden and identify challenges related to TB screening and diagnosis in Ethiopia. A facility-based cross-sectional study was conducted in seven health facilities selected from two regions and 2 city administrations of Ethiopia using stratified random sampling procedures. The data of 1,059,065 patients were included from outpatient department, HIV clinic, diabetic, and maternal-child health clinics. Data were collected from October to December 2018 using a retrospective review of three years' facility data (2015 to 2017) supplemented by a semi-structured interview with purposively selected health care workers and heads of the health facilities. A total of 1,059,065 patients visited the health facilities in three years, of these, 978,480 (92.4%) were outpatients. Of the total, 20,284 (2%) were presumptive TB cases The burden of TB was high in the study setting, and frequent interruption of laboratory reagents and supplies hampered TB screening and diagnostic services. Realizing the END-TB strategy in such resource-limited settings requires sustainable TB diagnostic capacity and improved case detection mechanisms, with national TB programs strongly integrated into the general health care system.
Identifiants
pubmed: 32258437
doi: 10.1016/j.jctube.2020.100158
pii: S2405-5794(20)30016-4
pii: 100158
pmc: PMC7113623
doi:
Types de publication
Journal Article
Langues
eng
Pagination
100158Subventions
Organisme : FIC NIH HHS
ID : D43 TW009127
Pays : United States
Organisme : Medical Research Council
ID : MR/M025470/1
Pays : United Kingdom
Informations de copyright
© 2020 The Authors.
Déclaration de conflit d'intérêts
Authors declared that there are no conflicts of interest.
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