Non-invasive diagnosis: non-alcoholic fatty liver disease and alcoholic liver disease.
Non-invasive diagnosis
alcoholic liver disease (ALD)
fibrosis
non-alcoholic fatty liver disease (NAFLD)
steatosis
Journal
Translational gastroenterology and hepatology
ISSN: 2415-1289
Titre abrégé: Transl Gastroenterol Hepatol
Pays: China
ID NLM: 101683450
Informations de publication
Date de publication:
2020
2020
Historique:
received:
10
07
2019
accepted:
30
10
2019
entrez:
8
4
2020
pubmed:
8
4
2020
medline:
8
4
2020
Statut:
epublish
Résumé
Non-alcoholic fatty liver disease (NAFLD) and alcoholic liver disease (ALD) are becoming the leading causes of chronic liver disease worldwide, significantly impacting public health and healthcare cost. The development of fibrosis is the main factor leading to early mortality and morbidity in NAFLD and ALD. Thus, it is important to timely and reliably evaluate these diseases at early stages, when fibrosis is not advanced or when steatosis predominates. Liver biopsy has been the standard of reference for fibrosis and steatosis, however, its invasiveness precludes its widespread use. There is growing research on non-invasive methods for diagnosing and stratifying fibrosis and steatosis in NAFLD and ALD. This review presents clinical evidence on the use of non-invasive assessment of liver disease (blood-based and imaging-based) in patients with NALFD and ALD, and proposes algorithms incorporating these tests into their management.
Identifiants
pubmed: 32258535
doi: 10.21037/tgh.2019.11.14
pii: tgh-05-2019.11.14
pmc: PMC7063491
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
31Informations de copyright
2020 Translational Gastroenterology and Hepatology. All rights reserved.
Déclaration de conflit d'intérêts
Conflicts of Interest: The authors have no conflicts of interest to declare.
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