Interictal magnetoencephalography in parietal lobe epilepsy - Comparison of equivalent current dipole and beamformer (SAMepi) analysis.
Beamformer
Epilepsy surgery
Equivalent current dipole
Interictal
Magnetoencephalography
Parietal lobe
Journal
Clinical neurophysiology practice
ISSN: 2467-981X
Titre abrégé: Clin Neurophysiol Pract
Pays: Netherlands
ID NLM: 101684308
Informations de publication
Date de publication:
2020
2020
Historique:
received:
17
07
2019
revised:
31
10
2019
accepted:
02
02
2020
entrez:
8
4
2020
pubmed:
8
4
2020
medline:
8
4
2020
Statut:
epublish
Résumé
To evaluate a novel analysis method (SAMepi) in the localization of interictal epileptiform magnetoencephalographic (MEG) activity in parietal lobe epilepsy (PLE) patients in comparison with equivalent current dipole (ECD) analysis. We analyzed the preoperative interictal MEG of 17 operated PLE patients utilizing visual analysis and: (1) ECD with a spherical conductor model; (2) ECD with a boundary element method (BEM) conductor model; and (3) SAMepi - a kurtosis beamformer method. Localization results were compared between the three methods, to the location of the resection and to the clinical outcome. Fourteen patients had an epileptiform finding in the visual analysis; SAMepi detected spikes in 11 of them. A unifocal finding in both the ECD and in the SAMepi analysis was associated with a better chance of seizure-freedom (p = 0.02). There was no significant difference in the distances from the unifocal MEG localizations to the nearest border of the resection between the different analysis methods. Localizations of unifocal interictal spikes detected by SAMepi did not significantly differ from the conventional ECD localizations. SAMepi - a novel semiautomatic analysis method - is useful in localizing interictal epileptiform MEG activity in the presurgical evaluation of parietal lobe epilepsy patients.
Identifiants
pubmed: 32258834
doi: 10.1016/j.cnp.2020.02.003
pii: S2467-981X(20)30008-1
pmc: PMC7118275
doi:
Types de publication
Journal Article
Langues
eng
Pagination
64-72Informations de copyright
© 2020 International Federation of Clinical Neurophysiology. Published by Elsevier B.V.
Déclaration de conflit d'intérêts
None.
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