Delta-Integration of Single Gene Shapes the Whole Metabolomic Short-Term Response to Ethanol of Recombinant
Consolidated Bioprocessing
FTIR
bioethanol
ethanol stress response
glucoamylase
industrial yeast engineering
liquid chromatography-mass spectrometry
metabolic burden
metabolomics
multivariate analysis
Journal
Metabolites
ISSN: 2218-1989
Titre abrégé: Metabolites
Pays: Switzerland
ID NLM: 101578790
Informations de publication
Date de publication:
03 Apr 2020
03 Apr 2020
Historique:
received:
28
02
2020
revised:
25
03
2020
accepted:
01
04
2020
entrez:
9
4
2020
pubmed:
9
4
2020
medline:
9
4
2020
Statut:
epublish
Résumé
In yeast engineering, metabolic burden is often linked to the reprogramming of resources from regular cellular activities to guarantee recombinant protein(s) production. Therefore, growth parameters can be significantly influenced. Two recombinant strains, previously developed by the multiple δ-integration of a glucoamylase in the industrial
Identifiants
pubmed: 32260275
pii: metabo10040140
doi: 10.3390/metabo10040140
pmc: PMC7241245
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Università degli Studi di Padova
ID : DOR1827441/18, DOR1824847/18 and DOR1931153/19.
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