Benzamide Derivatives Targeting the Cell Division Protein FtsZ: Modifications of the Linker and the Benzodioxane Scaffold and Their Effects on Antimicrobial Activity.
1,4-benzodioxane
1,4-benzoxathiane
Escherichia coli N43
benzamide
cell division protein FtsZ
multi-drug resistant Staphylococcus aureus
Journal
Antibiotics (Basel, Switzerland)
ISSN: 2079-6382
Titre abrégé: Antibiotics (Basel)
Pays: Switzerland
ID NLM: 101637404
Informations de publication
Date de publication:
04 Apr 2020
04 Apr 2020
Historique:
received:
03
03
2020
revised:
31
03
2020
accepted:
01
04
2020
entrez:
9
4
2020
pubmed:
9
4
2020
medline:
9
4
2020
Statut:
epublish
Résumé
Filamentous temperature-sensitive Z (FtsZ) is a prokaryotic protein with an essential role in the bacterial cell division process. It is widely conserved and expressed in both Gram-positive and Gram-negative strains. In the last decade, several research groups have pointed out molecules able to target FtsZ in
Identifiants
pubmed: 32260339
pii: antibiotics9040160
doi: 10.3390/antibiotics9040160
pmc: PMC7235863
pii:
doi:
Types de publication
Journal Article
Langues
eng
Références
Antibiotics (Basel). 2020 Feb 07;9(2):
pubmed: 32046082
Nat Rev Microbiol. 2016 Apr;14(5):305-19
pubmed: 27040757
J Med Chem. 2006 Oct 19;49(21):6177-96
pubmed: 17034125
Clin Microbiol Infect. 2004 Jan;10(1):12-26
pubmed: 14706082
J Med Chem. 2004 Mar 25;47(7):1739-49
pubmed: 15027865
Eur J Med Chem. 2015 Jan 7;89:252-65
pubmed: 25462242
Proc Natl Acad Sci U S A. 2004 Aug 10;101(32):11821-6
pubmed: 15289600
J Org Chem. 2018 Nov 2;83(21):13217-13227
pubmed: 30265535
Trends Cell Biol. 1997 Sep;7(9):362-7
pubmed: 17708981
Microbiol Spectr. 2016 Apr;4(2):
pubmed: 27227291
ChemMedChem. 2017 Aug 22;12(16):1303-1318
pubmed: 28586174
ChemMedChem. 2020 Jan 17;15(2):195-209
pubmed: 31750973
Lancet Infect Dis. 2018 Mar;18(3):318-327
pubmed: 29276051
Antimicrob Agents Chemother. 2001 Apr;45(4):1126-36
pubmed: 11257026
J Infect Dis. 2008 Apr 15;197(8):1079-81
pubmed: 18419525
Biochem Biophys Res Commun. 2014 Oct 17;453(2):254-67
pubmed: 24878531
Eur J Med Chem. 2016 Sep 14;120:227-43
pubmed: 27191617
Pharmacotherapy. 2017 Jan;37(1):71-84
pubmed: 27859453
Clin Microbiol Rev. 2006 Apr;19(2):382-402
pubmed: 16614254
Nat Rev Mol Cell Biol. 2005 Nov;6(11):862-71
pubmed: 16227976
Antimicrob Agents Chemother. 1999 Jun;43(6):1340-6
pubmed: 10348749
J Am Chem Soc. 2010 May 5;132(17):5926-7
pubmed: 20387895
J Mol Evol. 2004 Jan;58(1):19-29
pubmed: 14743312
Adv Enzymol Relat Areas Mol Biol. 2011;77:1-60
pubmed: 21692366
Biochem Pharmacol. 2014 Jun 1;89(3):321-8
pubmed: 24637241
J Comput Chem. 2005 Dec;26(16):1752-80
pubmed: 16211539
Antiviral Res. 2015 Apr;116:67-75
pubmed: 25660110
FEMS Microbiol Rev. 2019 Sep 1;43(5):490-516
pubmed: 31150547
Bioorg Med Chem Lett. 2009 Jan 15;19(2):524-7
pubmed: 19064318