Japanese guidelines for atopic dermatitis 2020.

Atopic dermatitis Clinical practice guidelines Eczema Evidence-based medicine Treatment

Journal

Allergology international : official journal of the Japanese Society of Allergology
ISSN: 1440-1592
Titre abrégé: Allergol Int
Pays: England
ID NLM: 9616296

Informations de publication

Date de publication:
Jul 2020
Historique:
received: 24 12 2019
revised: 26 02 2020
accepted: 26 02 2020
pubmed: 9 4 2020
medline: 20 8 2021
entrez: 9 4 2020
Statut: ppublish

Résumé

Atopic dermatitis (AD) is a disease characterized by relapsing eczema with pruritus as a primary lesion, which is frequently encountered in clinical practice. Skin barrier dysfunction leads to enhanced skin irritability to non-specific stimuli and epicutaneous sensitization. In the lesion site, a further inflammation-related reduction in skin barrier function, enhanced irritability and scratching-related stimuli deteriorate eczema, leading to vicious cycle of inflammation. The current strategies to treat AD in Japan from the perspective of evidence-based medicine consist of three primary measures: (i) the use of topical corticosteroids and tacrolimus ointment as the main treatment for the inflammation; (ii) topical application of emollients to treat the cutaneous barrier dysfunction; and (iii) avoidance of apparent exacerbating factors, psychological counseling and advice about daily life. The guidelines present recommendations to review clinical research articles, evaluate the balance between the advantages and disadvantages of medical activities, and optimize medical activity-related patient outcomes with respect to several important points requiring decision-making in clinical practice.

Identifiants

pubmed: 32265116
pii: S1323-8930(20)30018-6
doi: 10.1016/j.alit.2020.02.006
pii:
doi:

Types de publication

Journal Article Practice Guideline Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

356-369

Informations de copyright

Copyright © 2020 Japanese Society of Allergology. Production and hosting by Elsevier B.V. All rights reserved.

Auteurs

Norito Katoh (N)

Department of Dermatology, Kyoto Prefectural University of Medicine Graduate School of Medical Science, Kyoto, Japan. Electronic address: nkatoh@koto.kpu-m.ac.jp.

Yukihiro Ohya (Y)

Allergy Center, National Center for Child Health and Development, Tokyo, Japan.

Masanori Ikeda (M)

Department of Pediatric Acute Medicine, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan.

Tamotsu Ebihara (T)

Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.

Ichiro Katayama (I)

Department of Dermatology, Graduate School of Medicine, Osaka University, Suita, Japan.

Hidehisa Saeki (H)

Department of Dermatology, Graduate School of Medicine, Nihon Medical School, Tokyo, Japan.

Naoki Shimojo (N)

Department of Pediatrics, Graduate School of Medicine, Chiba University, Chiba, Japan.

Akio Tanaka (A)

Department of Dermatology, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan.

Takeshi Nakahara (T)

Division of Skin Surface Sensing, Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Mizuho Nagao (M)

Division of Clinical Research, National Hospital Organization Mie National Hospital, Tsu, Japan.

Michihiro Hide (M)

Department of Dermatology, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan.

Yuji Fujita (Y)

Department of Pediatrics, Graduate School of Medicine, Chiba University, Chiba, Japan.

Takao Fujisawa (T)

Division of Allergy, National Hospital Organization Mie National Hospital, Tsu, Japan.

Masaki Futamura (M)

Division of Pediatrics, National Hospital Organization Nagoya Medical Center, Nagoya, Japan.

Koji Masuda (K)

Department of Dermatology, Kyoto Prefectural University of Medicine Graduate School of Medical Science, Kyoto, Japan.

Hiroyuki Murota (H)

Department of Dermatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.

Kiwako Yamamoto-Hanada (K)

Allergy Center, National Center for Child Health and Development, Tokyo, Japan.

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