Adherence to follow-up recommendations for dogs with apocrine gland anal sac adenocarcinoma: A multicentre retrospective study.
Adenocarcinoma
/ pathology
Anal Gland Neoplasms
/ pathology
Anal Sacs
/ pathology
Animals
Antineoplastic Agents
/ therapeutic use
Apocrine Glands
/ pathology
Dog Diseases
/ pathology
Dogs
Neoplasm Staging
Patient Acceptance of Health Care
/ statistics & numerical data
Retrospective Studies
United States
adenocarcinoma
adherence
anal sac
screening
Journal
Veterinary and comparative oncology
ISSN: 1476-5829
Titre abrégé: Vet Comp Oncol
Pays: England
ID NLM: 101185242
Informations de publication
Date de publication:
Dec 2020
Dec 2020
Historique:
received:
09
12
2019
revised:
02
04
2020
accepted:
02
04
2020
pubmed:
9
4
2020
medline:
9
9
2021
entrez:
9
4
2020
Statut:
ppublish
Résumé
Progressive disease is common following anal sacculectomy for apocrine gland anal sac adenocarcinoma (AGASACA); additional therapy may prolong survival. Adherence to medical recommendations influences therapeutic success in humans. The purpose of this study was to assess the adherence to follow-up recommendations in dogs with AGASACA. Medical records of patients that underwent anal sacculectomy for AGASACA, with or without iliosacral lymphadenectomy, between July 2015 and July 2018, were reviewed at eight referral institutions to assess post-operative recommendations and owner adherence to recommendations. One hundred and seventy-four dogs were included, of which 162 underwent unilateral anal sacculectomy, 12 underwent bilateral anal sacculectomy and 39 underwent concurrent iliosacral lymphadenectomy. Seventy-six owners (44%) received recommendations for staging at the time of discharge, histopathology results or at the first follow-up visit. One hundred and forty owners (80%) received recommendations for treatment following the initial surgery. Fifty of seventy-six (66%) owners pursued at least one staging recommendation and 69 of 140 (49%) owners pursued some kind of adjuvant treatment recommendation. Overall, 16 of 76 (21%) were adherent to staging recommendations with 20 adherent for the first year following surgery (26%). Forty-seven of 140 (34%) were adherent to treatment recommendations with 54 (39%) adherent for the first year. Owners that were adherent to restaging recommendations at 1 year following surgery were significantly more likely to pursue treatment for progressive disease (P = .014). Further work is required to assess owner motivation and evaluate strategies to improve adherence, given the potential impact on patient treatment.
Substances chimiques
Antineoplastic Agents
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
683-688Informations de copyright
© 2020 John Wiley & Sons Ltd.
Références
Wouda R, Borrego J, Keuler N, Stein T. Evaluation of adjuvant carboplatin chemotherapy in the management of surgically excised anal sac apocrine gland adenocarcinoma in dogs. Vet Comp Oncol. 2013;14:67-80.
Bennett PF, DeNicola DB, Bonney P, Glickman NW, Knapp DW. Canine anal sac adenocarcinomas: clinical presentation and response to therapy. J Vet Intern Med. 2002;16:100-104.
Barnes D, Demetriou J. Surgical management of primary, metastatic and recurrent anal sac adenocarcinoma in the dog: 52 cases. J Small Anim Pract. 2017;58:263-268.
Hobson HI, Brown M, Rogers KS. Surgery of metastatic anal sac adenocarcinoma in five dogs. Vet Surg. 2006;35:267-270.
Liptak J. In: ACVS Surgery Summit. Nashville, TN: American College of Veterinary Surgeons; 2020:395-398.
Sabaté E, Sabaté E, eds. Adherence to Long-Term Therapies: Evidence for Action. Geneva, Switzerland: World Health Organization; 2003.
Manders DB, Morón A, McIntire D, et al. Locally advanced cervical cancer. Am J Clin Oncol. 2018;41:447-451.
Ayer T, Alagoz O, Stout NK, Burnside ES. Heterogeneity in women's adherence and its role in optimal breast cancer screening policies. Manage Sci. 2016;62:1339-1362.
Subramanian S, Klosterman M, Amonkar MM, Hunt TL. Adherence with colorectal cancer screening guidelines: a review. Prev Med. 2004;38:536-550.
Lerman C, Rimer B, Trock B, Balshem A, Engstrom PF. Factors associated with repeat adherence to breast cancer screening. Prev Med. 1990;19:279-290.
Montes U, Ijo L, Campo A, Caide A, Bastarrika G, Zulueta J. Factors determining early adherence to a lung cancer screening protocol. Eur Respir J. 2007;30:532-537.