Visualization of a Distributed Synaptic Memory Code in the Drosophila Brain.
Animals
Association Learning
/ physiology
Calcium
/ metabolism
Conditioning, Classical
Drosophila melanogaster
Memory
/ physiology
Microscopy, Confocal
Microscopy, Fluorescence
Mushroom Bodies
/ cytology
Neuronal Plasticity
Neurons
/ physiology
Odorants
Optical Imaging
Presynaptic Terminals
/ physiology
Smell
Synapses
Drosophila melanogaster
Kenyon cell
insect brain
learning and memory
mushroom body
neuronal assemblies
odor representation
olfactory coding
optical calcium imaging
synaptic plasticity
Journal
Neuron
ISSN: 1097-4199
Titre abrégé: Neuron
Pays: United States
ID NLM: 8809320
Informations de publication
Date de publication:
17 06 2020
17 06 2020
Historique:
received:
11
04
2019
revised:
19
11
2019
accepted:
13
03
2020
pubmed:
9
4
2020
medline:
22
9
2020
entrez:
9
4
2020
Statut:
ppublish
Résumé
During associative conditioning, animals learn which sensory cues are predictive for positive or negative conditions. Because sensory cues are encoded by distributed neurons, one has to monitor plasticity across many synapses to capture how learned information is encoded. We analyzed synaptic boutons of Kenyon cells of the Drosophila mushroom body γ lobe, a brain structure that mediates olfactory learning. A fluorescent Ca
Identifiants
pubmed: 32268119
pii: S0896-6273(20)30217-8
doi: 10.1016/j.neuron.2020.03.010
pii:
doi:
Substances chimiques
Calcium
SY7Q814VUP
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Video-Audio Media
Langues
eng
Sous-ensembles de citation
IM
Pagination
963-976.e4Commentaires et corrections
Type : CommentIn
Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Interests The authors declare no competing interests.