Network Implementation of Guideline for Early Detection Decreases Age at Cerebral Palsy Diagnosis.


Journal

Pediatrics
ISSN: 1098-4275
Titre abrégé: Pediatrics
Pays: United States
ID NLM: 0376422

Informations de publication

Date de publication:
05 2020
Historique:
accepted: 13 01 2020
pubmed: 10 4 2020
medline: 22 7 2020
entrez: 10 4 2020
Statut: ppublish

Résumé

Early diagnosis of cerebral palsy (CP) is critical in obtaining evidence-based interventions when plasticity is greatest. In 2017, international guidelines for early detection of CP were published on the basis of a systematic review of evidence. Our study aim was to reduce the age at CP diagnosis throughout a network of 5 diverse US high-risk infant follow-up programs through consistent implementation of these guidelines. The study leveraged plan-do-study-act and Lean methodologies. The primary outcome was age at CP diagnosis. Data were acquired during the corresponding 9-month baseline and quarterly throughout study. Balancing measures were clinic no-show rates and parent perception of the diagnosis visit. Clinic teams conducted strengths, weaknesses, opportunities, and threats analyses, process flow evaluations, standardized assessments training, and parent questionnaires. Performance of a 3- to 4-month clinic visit was a critical process step because it included a Hammersmith Infant Neurologic Examination, a General Movements Assessment, and standardized assessments of motor function. The age at CP diagnosis decreased from a weighted average of 19.5 (95% confidence interval 16.2 to 22.8) to 9.5 months (95% confidence interval 4.5 to 14.6), with Large-scale implementation of international guidelines for early detection of CP is feasible in diverse high-risk infant follow-up clinics. The initiative was received positively by families and without adversely affecting clinic operational flow. Additional parent support and education are necessary.

Sections du résumé

BACKGROUND AND OBJECTIVES
Early diagnosis of cerebral palsy (CP) is critical in obtaining evidence-based interventions when plasticity is greatest. In 2017, international guidelines for early detection of CP were published on the basis of a systematic review of evidence. Our study aim was to reduce the age at CP diagnosis throughout a network of 5 diverse US high-risk infant follow-up programs through consistent implementation of these guidelines.
METHODS
The study leveraged plan-do-study-act and Lean methodologies. The primary outcome was age at CP diagnosis. Data were acquired during the corresponding 9-month baseline and quarterly throughout study. Balancing measures were clinic no-show rates and parent perception of the diagnosis visit. Clinic teams conducted strengths, weaknesses, opportunities, and threats analyses, process flow evaluations, standardized assessments training, and parent questionnaires. Performance of a 3- to 4-month clinic visit was a critical process step because it included a Hammersmith Infant Neurologic Examination, a General Movements Assessment, and standardized assessments of motor function.
RESULTS
The age at CP diagnosis decreased from a weighted average of 19.5 (95% confidence interval 16.2 to 22.8) to 9.5 months (95% confidence interval 4.5 to 14.6), with
CONCLUSIONS
Large-scale implementation of international guidelines for early detection of CP is feasible in diverse high-risk infant follow-up clinics. The initiative was received positively by families and without adversely affecting clinic operational flow. Additional parent support and education are necessary.

Identifiants

pubmed: 32269135
pii: peds.2019-2126
doi: 10.1542/peds.2019-2126
pmc: PMC7193973
pii:
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NICHD NIH HHS
ID : R01 HD081120
Pays : United States

Informations de copyright

Copyright © 2020 by the American Academy of Pediatrics.

Déclaration de conflit d'intérêts

POTENTIAL CONFLICT OF INTEREST: The authors have indicated they have no potential conflicts of interest to disclose.

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Auteurs

Nathalie L Maitre (NL)

Center for Perinatal Research and nathalie.maitre@nationwidechildrens.org.
Department of Pediatrics, Nationwide Children's Hospital, Columbus, Ohio.

Vera J Burton (VJ)

Division of Neurology and Developmental Medicine, Kennedy Krieger Institute, Baltimore, Maryland.
Department of Pediatrics and Neurosciences Intensive Care Nursery, School of Medicine, Johns Hopkins University, Baltimore, Maryland.

Andrea F Duncan (AF)

Department of Pediatrics, The University of Texas Health Science Center at Houston, Houston, Texas.

Sai Iyer (S)

Program of Developmental Behavioral Pediatrics, Department of Pediatrics, Mattel Children's Hospital, and University of California, Los Angeles, Los Angeles, California.

Betsy Ostrander (B)

Department of Pediatrics, School of Medicine, University of Utah, Salt Lake City, Utah; and.

Sarah Winter (S)

Department of Pediatrics, School of Medicine, University of Utah, Salt Lake City, Utah; and.

Lauren Ayala (L)

Department of Pediatrics, School of Medicine, University of Utah, Salt Lake City, Utah; and.

Stephanie Burkhardt (S)

Center for Perinatal Research and.

Gwendolyn Gerner (G)

Division of Neurology and Developmental Medicine, Kennedy Krieger Institute, Baltimore, Maryland.
Department of Pediatrics and Neurosciences Intensive Care Nursery, School of Medicine, Johns Hopkins University, Baltimore, Maryland.

Ruth Getachew (R)

Division of Neurology and Developmental Medicine, Kennedy Krieger Institute, Baltimore, Maryland.

Kelsey Jiang (K)

Program of Developmental Behavioral Pediatrics, Department of Pediatrics, Mattel Children's Hospital, and University of California, Los Angeles, Los Angeles, California.

Laurie Lesher (L)

Department of Pediatrics, School of Medicine, University of Utah, Salt Lake City, Utah; and.

Carrie M Perez (CM)

Department of Pediatrics, The University of Texas Health Science Center at Houston, Houston, Texas.

Melissa Moore-Clingenpeel (M)

Biostatistics Core, The Abigail Wexner Research Institute, and.

Rebecca Lam (R)

Cerebral Palsy Foundation, New York, New York.

Dennis J Lewandowski (DJ)

Center for Perinatal Research and.

Rachel Byrne (R)

Cerebral Palsy Foundation, New York, New York.

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Classifications MeSH