Successful kidney transplantation in a patient with stable multiple myeloma.

end-stage kidney disease immunosuppression kidney transplantation multiple myeloma plasma cell dyscrasias renal insufficiency

Journal

Internal medicine journal
ISSN: 1445-5994
Titre abrégé: Intern Med J
Pays: Australia
ID NLM: 101092952

Informations de publication

Date de publication:
04 2020
Historique:
received: 15 05 2019
revised: 04 08 2019
accepted: 11 08 2019
entrez: 10 4 2020
pubmed: 10 4 2020
medline: 11 3 2021
Statut: ppublish

Résumé

Renal failure is a common feature of multiple myeloma affecting 20-55% of patients at the initial presentation and is being associated with a significant increase in morbidity and mortality. Renal transplantation for patients with multiple myeloma is rarely considered given the incurable nature of the disease, the risk of post-transplant disease progression and perceived high risk of infections. Here we report a 57-year-old man with end-stage renal failure attributed to presumed IgA nephropathy, with pre-existing stable multiple myeloma, who received a kidney transplant from a two haplotype-matched sibling. Transplantation has been successful and with excellent kidney function and stable multiple myeloma 6 years post-transplant. This case highlights the potential benefits of renal transplantation in highly selected patients with multiple myeloma.

Identifiants

pubmed: 32270609
doi: 10.1111/imj.14790
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

492-494

Informations de copyright

© 2020 Royal Australasian College of Physicians.

Auteurs

Christina Lai (C)

Department of Renal Medicine, Royal Prince Alfred Hospital, Sydney, Australia.
Kidney Node, Charles Perkins Centre, University of Sydney, Sydney, Australia.

Tracey Ying (T)

Department of Renal Medicine, Royal Prince Alfred Hospital, Sydney, Australia.
Kidney Node, Charles Perkins Centre, University of Sydney, Sydney, Australia.

P Joy Ho (PJ)

Institute of Haematology, Royal Prince Alfred Hospital, and University of Sydney, Sydney, Australia.

Kate Wyburn (K)

Department of Renal Medicine, Royal Prince Alfred Hospital, Sydney, Australia.
Kidney Node, Charles Perkins Centre, University of Sydney, Sydney, Australia.

Martin Gallagher (M)

The George Institute for Global Health, University of Sydney, Sydney, Australia.
Renal Medicine, Concord Repatriation General Hospital, Sydney, New South Wales, Australia.

Steve Chadban (S)

Department of Renal Medicine, Royal Prince Alfred Hospital, Sydney, Australia.
Kidney Node, Charles Perkins Centre, University of Sydney, Sydney, Australia.

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Classifications MeSH