Implant surface activates fibroblasts: an in vitro study.
expression
fibroblast
gene
implants
titanium
Journal
Journal of biological regulators and homeostatic agents
ISSN: 0393-974X
Titre abrégé: J Biol Regul Homeost Agents
Pays: Italy
ID NLM: 8809253
Informations de publication
Date de publication:
Historique:
entrez:
10
4
2020
pubmed:
10
4
2020
medline:
27
6
2020
Statut:
ppublish
Résumé
Titanium (Ti) is that the most generally used material for dental, orthopedic and maxillofacial purposes thanks to its excellent biocompatibility and mechanical properties. Several data suggest that prosthesis anchorage to bone and soft tissue are often modulated by surface characteristics. Fibroblasts are the soft tissues cells concerned in producing extracellular matrix and collagen and their tight connection to implant neck is of paramount importance in preventing peri-implant infection. The aim of this work is to grow Human Fibroblast (HFb) for seven days in wells containing (or not) dental implants. The expression levels of some adhesion and traction-resistance related genes (COL11A1, COL2A1, COL9A1, DSP, ELN, HAS1, and TFRC) were analyzed using Polymerase Chain Reaction. Our results demonstrated that several genes encoding for extracellular matrix proteins are activated so giving more insight to the comprehension of the mechanism of cell to surface adhesion.
Substances chimiques
Dental Implants
0
Collagen
9007-34-5
Titanium
D1JT611TNE
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
31-35. DENTAL SUPPLEMENTInformations de copyright
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