The Synthetic Cannabinoid URB447 Reduces Brain Injury and the Associated White Matter Demyelination after Hypoxia-Ischemia in Neonatal Rats.
Hypoxia-ischemia
SR141716A
URB447
cannabinoids
neuroprotection
white matter demyelination
Journal
ACS chemical neuroscience
ISSN: 1948-7193
Titre abrégé: ACS Chem Neurosci
Pays: United States
ID NLM: 101525337
Informations de publication
Date de publication:
06 05 2020
06 05 2020
Historique:
pubmed:
10
4
2020
medline:
22
6
2021
entrez:
10
4
2020
Statut:
ppublish
Résumé
The number of functions controlled by the endocannabinoid system in health and disease continues growing over the years. In the brain, these include the modulation of harmful events such as glutamate excitotoxicity, oxidative stress, and inflammation, mainly regulated by activation/blockade of CB
Identifiants
pubmed: 32271539
doi: 10.1021/acschemneuro.0c00047
pmc: PMC7997380
doi:
Substances chimiques
(4-amino-1-(4-chlorobenzyl)-2-methyl-5-phenyl-1H-pyrrol-3-yl)(phenyl)methanone
0
Benzyl Compounds
0
Cannabinoids
0
Pyrroles
0
Receptor, Cannabinoid, CB1
0
Receptor, Cannabinoid, CB2
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1291-1299Références
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