Developmental changes in attention to social information from childhood to adolescence in autism spectrum disorders: a comparative study.

Adolescent Attention Autism Spectrum Disorder / psychology Child Child, Preschool Female Fixation, Ocular Humans Male Social Behavior
Autism spectrum disorder Developmental change Eye-tracking Social information

Journal

Molecular autism
ISSN: 2040-2392
Titre abrégé: Mol Autism
Pays: England
ID NLM: 101534222

Informations de publication

Date de publication:
09 04 2020
Historique:
received: 25 05 2019
accepted: 07 02 2020
entrez: 11 4 2020
pubmed: 11 4 2020
medline: 1 1 2021
Statut: epublish

Résumé

Elucidating developmental changes in the symptoms of autism spectrum disorder (ASD) is important to support individuals with ASD. However, no report has clarified the developmental changes in attention to social information for a broad age range. The aim of this study was to investigate the developmental changes in attention to social information from early childhood to adolescence in individuals with ASD and typically developed (TD) children. We recruited children with ASD (n = 83) and TD participants (n = 307) between 2 and 18 years of age. Using the all-in-one-eye-tracking system, Gazefinder, we measured the percentage fixation time allocated to areas of interest (AoIs) depicted in movies (the eyes and mouth in movies of a human face with/without mouth motion, upright and inverted biological motion in movies showing these stimuli simultaneously, people and geometry in preference paradigm movies showing these stimuli simultaneously, and objects with/without finger-pointing in a movie showing a woman pointing toward an object). We conducted a three-way analysis of variance, 2 (diagnosis: ASD and TD) by 2 (sex: male and female) by 3 (age group: 0-5, 6-11, and 12-18 years) and locally weighted the scatterplot smoothing (LOESS) regression curve on each AoI. In the face stimuli, the percentage fixation time to the eye region for the TD group increased with age, whereas the one for the ASD group did not. In the ASD group, the LOESS curves of the gaze ratios at the eye region increased up to approximately 10 years of age and thereafter tended to decrease. For the percentage fixation time to the people region in the preference paradigm, the ASD group gazed more briefly at people than did the TD group. It is possible that due to the cross-sectional design, the degree of severity and of social interest might have differed according to the subjects' age. There may be qualitative differences in abnormal eye contact in ASD between individuals in early childhood and those older than 10 years.

Sections du résumé

BACKGROUND
Elucidating developmental changes in the symptoms of autism spectrum disorder (ASD) is important to support individuals with ASD. However, no report has clarified the developmental changes in attention to social information for a broad age range. The aim of this study was to investigate the developmental changes in attention to social information from early childhood to adolescence in individuals with ASD and typically developed (TD) children.
METHODS
We recruited children with ASD (n = 83) and TD participants (n = 307) between 2 and 18 years of age. Using the all-in-one-eye-tracking system, Gazefinder, we measured the percentage fixation time allocated to areas of interest (AoIs) depicted in movies (the eyes and mouth in movies of a human face with/without mouth motion, upright and inverted biological motion in movies showing these stimuli simultaneously, people and geometry in preference paradigm movies showing these stimuli simultaneously, and objects with/without finger-pointing in a movie showing a woman pointing toward an object). We conducted a three-way analysis of variance, 2 (diagnosis: ASD and TD) by 2 (sex: male and female) by 3 (age group: 0-5, 6-11, and 12-18 years) and locally weighted the scatterplot smoothing (LOESS) regression curve on each AoI.
RESULTS
In the face stimuli, the percentage fixation time to the eye region for the TD group increased with age, whereas the one for the ASD group did not. In the ASD group, the LOESS curves of the gaze ratios at the eye region increased up to approximately 10 years of age and thereafter tended to decrease. For the percentage fixation time to the people region in the preference paradigm, the ASD group gazed more briefly at people than did the TD group.
LIMITATIONS
It is possible that due to the cross-sectional design, the degree of severity and of social interest might have differed according to the subjects' age.
CONCLUSIONS
There may be qualitative differences in abnormal eye contact in ASD between individuals in early childhood and those older than 10 years.

Identifiants

DOI: 10.1186/s13229-020-00321-w PMID: 32272970 PMC: PMC7146883
pubmed: 32272970
doi: 10.1186/s13229-020-00321-w
pii: 10.1186/s13229-020-00321-w
pmc: PMC7146883
doi:

Types de publication

Comparative Study Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

24

Références

Arch Gen Psychiatry. 2008 Aug;65(8):946-54
pubmed: 18678799
Trends Cogn Sci. 2012 Apr;16(4):231-9
pubmed: 22425667
Neurosci Biobehav Rev. 2014 Feb;39:1-33
pubmed: 24361967
Sci Rep. 2017 May 31;7(1):2540
pubmed: 28566712
Neuropsychologia. 2007 Jun 18;45(11):2580-8
pubmed: 17459428
J Autism Dev Disord. 2012 Mar;42(3):401-8
pubmed: 21547412
J Neurosci. 2006 Mar 15;26(11):2894-906
pubmed: 16540566
Soc Dev. 2016 Nov;25(4):687-703
pubmed: 27795619
J Autism Dev Disord. 2002 Apr;32(2):69-75
pubmed: 12058845
J Autism Dev Disord. 2008 Oct;38(9):1666-75
pubmed: 18306030
J Autism Dev Disord. 2003 Dec;33(6):565-81
pubmed: 14714927
Autism Res. 2017 May;10(5):852-865
pubmed: 28256099
Int J Behav Dev. 2013 Mar;37(2):131-6
pubmed: 23585703
J Child Psychol Psychiatry. 2012 Aug;53(8):903-13
pubmed: 22428993
PLoS One. 2015 Mar 17;10(3):e0122280
pubmed: 25781170
J Child Psychol Psychiatry. 2002 Jul;43(5):669-78
pubmed: 12120862
Front Neurosci. 2014 Sep 17;8:295
pubmed: 25278829
Front Psychiatry. 2016 Aug 24;7:143
pubmed: 27605914
Psychol Sci. 2003 Mar;14(2):151-7
pubmed: 12661677
J Autism Dev Disord. 2008 Mar;38(3):574-80
pubmed: 17968644
Mol Autism. 2018 Mar 21;9:19
pubmed: 29581878
Mol Autism. 2016 Mar 23;7:19
pubmed: 27011784
Biol Psychiatry. 2016 Apr 15;79(8):657-66
pubmed: 25981170
Autism. 2007 May;11(3):265-77
pubmed: 17478579
Neuropsychologia. 2009 Jan;47(1):248-57
pubmed: 18706434
J Autism Dev Disord. 2009 Dec;39(12):1663-72
pubmed: 19590943
Neuropsychologia. 2008 Jan 15;46(1):137-47
pubmed: 17920642
Biol Psychiatry. 2014 Feb 1;75(3):231-7
pubmed: 23954107
Res Dev Disabil. 2016 Jan;48:79-93
pubmed: 26547134
Nature. 2009 May 14;459(7244):257-61
pubmed: 19329996
J Autism Dev Disord. 2017 Dec;47(12):3814-3821
pubmed: 28000078
Dev Sci. 2009 Sep;12(5):798-814
pubmed: 19702771
Arch Gen Psychiatry. 2011 Jan;68(1):101-9
pubmed: 20819977
Brain Res. 2011 Mar 22;1380:246-54
pubmed: 21129365
CNS Spectr. 2014 Apr;19(2):157-64
pubmed: 24352005
J Am Acad Child Adolesc Psychiatry. 2012 Mar;51(3):238-48
pubmed: 22365460
Q J Exp Psychol (Hove). 2008 Jul;61(7):986-98
pubmed: 18938281
J Autism Dev Disord. 2014 Dec;44(12):3063-71
pubmed: 24958436
PLoS One. 2013 Jul 08;8(7):e68816
pubmed: 23861945
Nat Neurosci. 2005 Apr;8(4):519-26
pubmed: 15750588
J Autism Dev Disord. 2002 Aug;32(4):249-61
pubmed: 12199131
PLoS One. 2013 Aug 26;8(8):e74017
pubmed: 23991212
Front Psychol. 2015 Jul 16;6:989
pubmed: 26236264
Biol Psychiatry. 2006 Mar 1;59(5):424-9
pubmed: 16256956
Pediatrics. 2012 May;129(5):e1112-20
pubmed: 22473372
Biol Psychiatry. 2013 Aug 1;74(3):195-203
pubmed: 23313640
Trends Cogn Sci. 2009 Mar;13(3):127-34
pubmed: 19217822
J Anxiety Disord. 2003;17(1):33-44
pubmed: 12464287
Sci Rep. 2017 Jun 9;7(1):3163
pubmed: 28600558
Nature. 2015 Jan 15;517(7534):284-92
pubmed: 25592533
Pediatrics. 2012 Jun;129(6):e1453-60
pubmed: 22641752
Int J Lang Commun Disord. 2003 Jul-Sep;38(3):265-85
pubmed: 12851079
J Autism Dev Disord. 2012 Oct;42(10):2236-45
pubmed: 22354708
PLoS One. 2017 May 4;12(5):e0175912
pubmed: 28472111
Acta Psychiatr Scand. 2013 Jul;128(1):45-53
pubmed: 23171198
Front Psychol. 2018 Aug 28;9:1587
pubmed: 30210410
IEEE Trans Image Process. 2007 May;16(5):1457-69
pubmed: 17491473
Arch Gen Psychiatry. 2002 Sep;59(9):809-16
pubmed: 12215080
Res Dev Disabil. 2011 Sep-Oct;32(5):1910-7
pubmed: 21515028
Soc Cogn Affect Neurosci. 2014 Jan;9(1):106-17
pubmed: 23596190
Proc Biol Sci. 2010 Oct 7;277(1696):2935-43
pubmed: 20484237
Arch Gen Psychiatry. 1992 Apr;49(4):282-8
pubmed: 1558462

Auteurs

Toru Fujioka (T)

Department of Science of Human Development, Humanities and Social Science, Faculty of Education, University of Fukui, Fukui, Fukui, Japan.
Research Center for Child Mental Development, University of Fukui, Eiheiji, Fukui, Japan.
Department of Child Development, United Graduate School of Child Development, Osaka University, Kanazawa University, Hamamatsu University School of Medicine, Chiba University, and University of Fukui, Suita, Osaka, Japan.

Kenji J Tsuchiya (KJ)

Department of Child Development, United Graduate School of Child Development, Osaka University, Kanazawa University, Hamamatsu University School of Medicine, Chiba University, and University of Fukui, Suita, Osaka, Japan.
Research Center for Child Mental Development, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan.

Manabu Saito (M)

Department of Neuropsychiatry, Graduate School of Medicine, Hirosaki University, Hirosaki, Aomori, Japan.

Yoshiyuki Hirano (Y)

Department of Child Development, United Graduate School of Child Development, Osaka University, Kanazawa University, Hamamatsu University School of Medicine, Chiba University, and University of Fukui, Suita, Osaka, Japan.
Research Center for Child Mental Development, Chiba University, Chiba, Chiba, Japan.

Muneaki Matsuo (M)

Department of Pediatrics, Faculty of Medicine, Saga University, Saga, Saga, Japan.

Mitsuru Kikuchi (M)

Department of Child Development, United Graduate School of Child Development, Osaka University, Kanazawa University, Hamamatsu University School of Medicine, Chiba University, and University of Fukui, Suita, Osaka, Japan.
Research Center for Child Mental Development, Kanazawa University, Kanazawa, Ishikawa, Japan.

Yoshihiro Maegaki (Y)

Division of Child Neurology, Department of Brain and Neurosciences, Faculty of Medicine, Tottori University, Yonago, Tottori, Japan.

Damee Choi (D)

Department of Child Development, United Graduate School of Child Development, Osaka University, Kanazawa University, Hamamatsu University School of Medicine, Chiba University, and University of Fukui, Suita, Osaka, Japan.
Research Center for Child Mental Development, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan.

Sumi Kato (S)

Department of Neuropsychiatry, Graduate School of Medicine, Hirosaki University, Hirosaki, Aomori, Japan.

Tokiko Yoshida (T)

Research Center for Child Mental Development, Chiba University, Chiba, Chiba, Japan.

Yuko Yoshimura (Y)

Institute of Human and Social Sciences, Kanazawa University, Kanazawa, Ishikawa, Japan.

Sawako Ooba (S)

Tottori University Hospital, Yonago, Tottori, Japan.

Yoshifumi Mizuno (Y)

Department of Child and Adolescent Psychological Medicine, University of Fukui Hospital, Eiheiji, Fukui, Japan.

Shinichiro Takiguchi (S)

Department of Child Development, United Graduate School of Child Development, Osaka University, Kanazawa University, Hamamatsu University School of Medicine, Chiba University, and University of Fukui, Suita, Osaka, Japan.
Department of Child and Adolescent Psychological Medicine, University of Fukui Hospital, Eiheiji, Fukui, Japan.

Hideo Matsuzaki (H)

Research Center for Child Mental Development, University of Fukui, Eiheiji, Fukui, Japan.
Department of Child Development, United Graduate School of Child Development, Osaka University, Kanazawa University, Hamamatsu University School of Medicine, Chiba University, and University of Fukui, Suita, Osaka, Japan.

Akemi Tomoda (A)

Research Center for Child Mental Development, University of Fukui, Eiheiji, Fukui, Japan.
Department of Child Development, United Graduate School of Child Development, Osaka University, Kanazawa University, Hamamatsu University School of Medicine, Chiba University, and University of Fukui, Suita, Osaka, Japan.

Katsuyuki Shudo (K)

Development Center, Healthcare Business Division, JVCKENWOOD Corporation, Yokohama, Kanagawa, Japan.

Masaru Ninomiya (M)

Development Center, Healthcare Business Division, JVCKENWOOD Corporation, Yokohama, Kanagawa, Japan.

Taiichi Katayama (T)

Department of Child Development, United Graduate School of Child Development, Osaka University, Kanazawa University, Hamamatsu University School of Medicine, Chiba University, and University of Fukui, Suita, Osaka, Japan.

Hirotaka Kosaka (H)

Research Center for Child Mental Development, University of Fukui, Eiheiji, Fukui, Japan. hirotaka@u-fukui.ac.jp.
Department of Child Development, United Graduate School of Child Development, Osaka University, Kanazawa University, Hamamatsu University School of Medicine, Chiba University, and University of Fukui, Suita, Osaka, Japan. hirotaka@u-fukui.ac.jp.
Department of Neuropsychiatry, Faculty of Medical Sciences, University of Fukui, Eiheiji, Fukui, Japan. hirotaka@u-fukui.ac.jp.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adolescent › Developmental changes in attention to social...
questionsmedicales.fr › Phénomènes psychologiques › Attention › Developmental changes in attention to social...
questionsmedicales.fr › Troubles mentaux › Troubles du développement neurologique › Troubles généralisés du développement de l'enfant › Trouble du spectre autistique › Developmental changes in attention to social...
questionsmedicales.fr › Personnes › Tranches d'âge › Enfant › Developmental changes in attention to social...
questionsmedicales.fr › Personnes › Tranches d'âge › Enfant › Enfant d'âge préscolaire › Developmental changes in attention to social...
questionsmedicales.fr › Phénomènes physiologiques oculaires › Mouvements oculaires › Fixation oculaire › Developmental changes in attention to social...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Developmental changes in attention to social...
questionsmedicales.fr › Comportement et mécanismes comportementaux › Comportement › Comportement social › Developmental changes in attention to social...