Round Spermatid Injection.
Assisted reproductive technology
Azoospermia
In vitro fertilization
Male factor infertility
Round spermatid injection
Testicular sperm extraction
Journal
The Urologic clinics of North America
ISSN: 1558-318X
Titre abrégé: Urol Clin North Am
Pays: United States
ID NLM: 0423221
Informations de publication
Date de publication:
May 2020
May 2020
Historique:
entrez:
11
4
2020
pubmed:
11
4
2020
medline:
6
5
2020
Statut:
ppublish
Résumé
From a fertility perspective, men with azoospermia represent a challenging patient population. When no mature spermatozoa are obtained during a testicular sperm extraction, patients are often left with limited options, such as adoption or the use of donor sperm. However, it has been reported that round spermatids can be successfully injected into human oocytes and used as an alternative to mature spermatozoa. This technique is known as round spermatid injection (ROSI). Despite the limitations of ROSI and diminished clinical success rates, the use of round spermatids for fertilization may have potential as a treatment modality for men with azoospermia.
Identifiants
pubmed: 32272989
pii: S0094-0143(19)30111-9
doi: 10.1016/j.ucl.2019.12.004
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
175-183Informations de copyright
Published by Elsevier Inc.