Alleviation of notalgia paresthetica with duloxetine after several lines offailed treatment: A case report.

Duloxetine Neurogenic itch Notalgia Paresthetica Pruritus

Journal

Case reports in women's health
ISSN: 2214-9112
Titre abrégé: Case Rep Womens Health
Pays: Netherlands
ID NLM: 101682122

Informations de publication

Date de publication:
Apr 2020
Historique:
received: 18 02 2020
revised: 23 03 2020
accepted: 24 03 2020
entrez: 11 4 2020
pubmed: 11 4 2020
medline: 11 4 2020
Statut: epublish

Résumé

Chronic pruritus affects up to 20% of the population; about 8% of patients suffer from neurogenic pruritus, including notalgia paresthetica (NP). This is a syndrome of benign, chronic itch of the unilateral medial border of the scapula of unknown etiology and limited treatment efficacy. Here we report the background on NP, followed by a classic case presentation of a 63-year-old woman. We report on difficulty in her diagnosis and numerous failed lines of treatment, until initiation of treatment with duloxetine, which provided her with long-lasting benefit for the first time. Delay in diagnosis is common for NP, and though there are many options for treatment, evidence is lacking to support their efficacy. Finding an effective, well-tolerated regimen to alleviate long-term suffering brought on by this syndrome is heavily dependent on early identification. Our case provides anecdotal evidence for both treatment efficacy as well as the etiology of this poorly understood phenomenon.

Identifiants

pubmed: 32274333
doi: 10.1016/j.crwh.2020.e00197
pii: S2214-9112(20)30027-8
pii: e00197
pmc: PMC7132164
doi:

Types de publication

Case Reports

Langues

eng

Pagination

e00197

Informations de copyright

© 2020 Published by Elsevier B.V.

Références

J Am Acad Dermatol. 2014 Jun;70(6):1139-41
pubmed: 24831319
Acta Clin Croat. 2018 Dec;57(4):721-725
pubmed: 31168209
Actas Dermosifiliogr. 2014 Jan-Feb;105(1):74-7
pubmed: 24378421
J Dermatol. 2007 May;34(5):315-9
pubmed: 17408440
J Am Acad Dermatol. 2001 Oct;45(4):630-2
pubmed: 11568762
J Am Acad Dermatol. 2005 Jun;52(6):1085-7
pubmed: 15928634
J Dermatolog Treat. 2019 Apr 3;:1-9
pubmed: 30942103

Auteurs

Amnon A Berger (AA)

Department of Anesthesia, Critical Case and Pain Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, United States of America.

Ivan Urits (I)

Department of Anesthesia, Critical Case and Pain Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, United States of America.

Jamal Hasoon (J)

Department of Anesthesia, Critical Case and Pain Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, United States of America.

Thomas Simopoulos (T)

Department of Anesthesia, Critical Case and Pain Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, United States of America.

Classifications MeSH