Ozone efficacy for the control of airborne viruses: Bacteriophage and norovirus models.
Journal
PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081
Informations de publication
Date de publication:
2020
2020
Historique:
received:
31
10
2019
accepted:
17
03
2020
entrez:
11
4
2020
pubmed:
11
4
2020
medline:
11
7
2020
Statut:
epublish
Résumé
This study was designed to test the efficacy of an air treatment using ozone and relative humidity (RH) for the inactivation of airborne viruses. Four phages (φX174, PR772, MS2 and φ6) and one eukaryotic virus (murine norovirus MNV-1) were exposed to low ozone concentrations (1.23 ppm for phages and 0.23 ppm for MNV-1) and various levels of RH for 10 to 70 minutes. The inactivation of these viruses was then assessed to determine which of the tested conditions provided the greatest reduction in virus infectivity. An inactivation of at least two orders of magnitude for φX174, MS2 and MNV-1 was achieved with an ozone exposure of 40 minutes at 85% RH. For PR772 and φ6, exposure to the reference condition at 20% RH for 10 minutes yielded the same results. These findings suggest that ozone used at a low concentration is a powerful disinfectant for airborne viruses when combined with a high RH. Air treatment could therefore be implemented inside hospital rooms ventilated naturally.
Identifiants
pubmed: 32275685
doi: 10.1371/journal.pone.0231164
pii: PONE-D-19-30387
pmc: PMC7147755
doi:
Substances chimiques
Disinfectants
0
Ozone
66H7ZZK23N
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e0231164Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
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