Differences in Brain Volume between Metabolically Healthy and Unhealthy Overweight and Obese Children: The Role of Fitness.

academic achievement cardiorespiratory fitness global volume gray matter regional volume

Journal

Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588

Informations de publication

Date de publication:
08 Apr 2020
Historique:
received: 22 02 2020
revised: 01 04 2020
accepted: 02 04 2020
entrez: 12 4 2020
pubmed: 12 4 2020
medline: 12 4 2020
Statut: epublish

Résumé

The aim of this study was to examine whether metabolically healthy overweight/obese children have greater global and regional gray matter volumes than their metabolically unhealthy peers. We further examined the association between gray matter volume and academic achievement, along with the role of cardiorespiratory fitness in these associations. A total of 97 overweight/obese children (10.0 ± 1.2 years) participated. We classified children as metabolically healthy/unhealthy based on metabolic syndrome cut-offs. Global and regional brain volumes were assessed by magnetic resonance imaging. Academic achievement was assessed using the Woodcock-Muñoz standardized test. Cardiorespiratory fitness was assessed by the 20 m shuttle run test. Metabolically healthy overweight/obese (MHO) children had greater regional gray matter volume compared to those who were metabolically unhealthy (MUO) (all

Identifiants

DOI: 10.3390/jcm9041059 PMID: 32276395 PMC: PMC7231256
pubmed: 32276395
pii: jcm9041059
doi: 10.3390/jcm9041059
pmc: PMC7231256
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Spanish Ministry of Economy and Competitiveness and the "Fondo Europeo de Desarrollo Regional (FEDER)"
ID : DEP2013-47540, DEP2016-79512-R and RYC-2011-09011
Organisme : Ministerio de Ciencia e Innovación
ID : FJC2018-037925-I
Organisme : Fundación Alicia Koplowitz
ID : -
Organisme : Spanish Ministry of Education, Culture and Sport
ID : FPU15/02645 and FPU14/06837
Organisme : Strategic Research Area Health Care Science, Karolinska Institutet/Umeå University
ID : -
Organisme : University of Granada, Plan Propio de Investigación 2016, Excellence actions: Units of Excellence, Unit of Excellence on Exercise and Health (UCEES); the European Union's Horizon 2020 research and innovation programme under grant agreement No 667302; the
ID : -
Organisme : European Regional Development Fund (ERDF)
ID : Ref. RD16/0022
Organisme : EXERNET Research Network on Exercise and Health in Special Populations
ID : DEP2005-00046/ACTI
Organisme : Junta de Andalucia, Consejeria de Conocimiento, Investigación y Universidades
ID : -

Déclaration de conflit d'intérêts

The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.

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Auteurs

Cristina Cadenas-Sanchez (C)

PROFITH "PROmoting FITness and Health through physical activity" research group, Department of Physical and Sports Education, Faculty of Sport Sciences, University of Granada, 18071 Granada, Spain.
MOVE-IT research group, Department of Physical Education, Faculty of Education Sciences University of Cádiz, 11519 Cádiz, Spain.
Institute for Innovation & Sustainable Development in Food Chain (IS-FOOD), Public University of Navarra, 31006 Pamplona, Spain.

Irene Esteban-Cornejo (I)

PROFITH "PROmoting FITness and Health through physical activity" research group, Department of Physical and Sports Education, Faculty of Sport Sciences, University of Granada, 18071 Granada, Spain.
Center for Cognitive and Brain Health, Department of Psychology, Northeastern University, Boston, MA 02115, USA.

Jairo H Migueles (JH)

PROFITH "PROmoting FITness and Health through physical activity" research group, Department of Physical and Sports Education, Faculty of Sport Sciences, University of Granada, 18071 Granada, Spain.

Idoia Labayen (I)

Institute for Innovation & Sustainable Development in Food Chain (IS-FOOD), Public University of Navarra, 31006 Pamplona, Spain.

Juan Verdejo-Román (J)

Mind, Brain and Behavior Research Center (CIMCYC), University of Granada, 18011 Granada, Spain.
Laboratory of Cognitive and Computational Neuroscience (UCM-UPM), Center for Biomedical Technology (CTB), Pozuelo de Alarcón, 28223 Madrid, Spain.

Jose Mora-Gonzalez (J)

PROFITH "PROmoting FITness and Health through physical activity" research group, Department of Physical and Sports Education, Faculty of Sport Sciences, University of Granada, 18071 Granada, Spain.
College of Health and Human Services, University of North Carolina at Charlotte, Charlotte, NC 28233, USA.

Pontus Henriksson (P)

Department of Biosciences and Nutrition at NOVUM, Karolinska Institutet, 14183 Huddinge, Sweden.
Department of Health, Medicine and Caring Sciences, Linköping University, 58183 Linköping, Sweden.

José Maldonado (J)

Department of Pediatrics, School of Medicine, University of Granada, 18016 Granada, Spain.
The Institute of Biomedicine Research (Instituto de Investigación Biosanitaria (IBS)), 18014 Granada, Spain.

José Gómez-Vida (J)

Department of Pediatrics, San Cecilio Hospital, 18016 Granada, Spain.

Charles H Hillman (CH)

Center for Cognitive and Brain Health, Department of Psychology, Northeastern University, Boston, MA 02115, USA.
Department of Physical Therapy, Movement, & Rehabilitation Sciences, Northeastern University, Boston, MA 02115, USA.

Kirk I Erickson (KI)

Brain Aging & Cognitive Health Lab, Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA.

Arthur F Kramer (AF)

Center for Cognitive and Brain Health, Department of Psychology, Northeastern University, Boston, MA 02115, USA.
Beckman Institute, University of Illinois at Urbana-Champaign, Champaign, IL 61801, USA.

Andrés Catena (A)

Department of Experimental Psychology, Mind, Brain and Behavior Research Center (CIMCYC), University of Granada, 18011 Granada, Spain.

Francisco B Ortega (FB)

PROFITH "PROmoting FITness and Health through physical activity" research group, Department of Physical and Sports Education, Faculty of Sport Sciences, University of Granada, 18071 Granada, Spain.
Department of Biosciences and Nutrition at NOVUM, Karolinska Institutet, 14183 Huddinge, Sweden.

Classifications MeSH