Functional imaging of the piriform cortex in focal epilepsy.


Journal

Experimental neurology
ISSN: 1090-2430
Titre abrégé: Exp Neurol
Pays: United States
ID NLM: 0370712

Informations de publication

Date de publication:
08 2020
Historique:
received: 12 03 2019
revised: 26 01 2020
accepted: 08 04 2020
pubmed: 13 4 2020
medline: 2 2 2021
entrez: 13 4 2020
Statut: ppublish

Résumé

Experiments in animal models have identified specific brain regions such as the deep anterior piriform cortex as important for controlling the initiation or propagation of both generalized and focal seizure activity. However, there is little experimental evidence to translate these observations to the control of focal seizures in humans. Here, we summarize findings from different hemodynamic and neurotransmitter functional imaging studies in groups of patients with focal epilepsies arising from different cortical locations in support of a common area of brain dysfunction in focal epilepsies.

Identifiants

pubmed: 32278645
pii: S0014-4886(20)30136-9
doi: 10.1016/j.expneurol.2020.113305
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

113305

Subventions

Organisme : Medical Research Council
ID : MR/L013215/1
Pays : United Kingdom

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Auteurs

Matthias Koepp (M)

Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, and MRI Unit, National Society for Epilepsy, Chalfont St Peter, Buckinghamshire, UK. Electronic address: m.koepp@ucl.ac.uk.

Marian Galovic (M)

Department of Neurology, University Hospital Zurich, Switzerland.

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Classifications MeSH