A Comparison of Treatments and Outcomes for Medullary versus Nonmedullary Colon Cancer: A Single Institutional Experience Showing a Worse Prognosis for Stage 3 Disease.
Journal
Surgery research and practice
ISSN: 2356-7759
Titre abrégé: Surg Res Pract
Pays: United States
ID NLM: 101628730
Informations de publication
Date de publication:
2020
2020
Historique:
received:
11
06
2019
revised:
06
01
2020
accepted:
17
02
2020
entrez:
14
4
2020
pubmed:
14
4
2020
medline:
14
4
2020
Statut:
epublish
Résumé
Prior studies have shown a better prognosis with medullary colon cancer (MCC) compared to nonmedullary colon carcinomas (NMC); however, data are inconsistent and lacking the evaluation of treatments received. As we did not see similar survival outcomes, we aimed to retrospectively examine survival and receipt of treatment differences between MCC and NMC within the Geisinger Health System. The Cancer Registry was retrospectively reviewed for MCC and NMC from 2006 to 2017. Demographics and treatments were compared using 33 MCC and 1775 NMC patients were identified and 31 (93.9%) MCC and 1433 (87.0%) NMC underwent resection. MCC were older ( Multiple previous studies showed a better prognosis for MCC compared to PD/UD NMC. We, however, found stage 3 patients had a worse prognosis which may be secondary to higher comorbidities, increased stage, and higher rate of UD.
Sections du résumé
BACKGROUND
BACKGROUND
Prior studies have shown a better prognosis with medullary colon cancer (MCC) compared to nonmedullary colon carcinomas (NMC); however, data are inconsistent and lacking the evaluation of treatments received. As we did not see similar survival outcomes, we aimed to retrospectively examine survival and receipt of treatment differences between MCC and NMC within the Geisinger Health System.
METHODS
METHODS
The Cancer Registry was retrospectively reviewed for MCC and NMC from 2006 to 2017. Demographics and treatments were compared using
RESULTS
RESULTS
33 MCC and 1775 NMC patients were identified and 31 (93.9%) MCC and 1433 (87.0%) NMC underwent resection. MCC were older (
CONCLUSION
CONCLUSIONS
Multiple previous studies showed a better prognosis for MCC compared to PD/UD NMC. We, however, found stage 3 patients had a worse prognosis which may be secondary to higher comorbidities, increased stage, and higher rate of UD.
Identifiants
pubmed: 32280741
doi: 10.1155/2020/5783729
pmc: PMC7142354
doi:
Types de publication
Journal Article
Langues
eng
Pagination
5783729Informations de copyright
Copyright © 2020 A. Gupta et al.
Déclaration de conflit d'intérêts
The authors declares that there are no conflicts of interest regarding the publication of this paper.
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