Trends in Treatment and Survival of Gallbladder Cancer in the Netherlands; Identifying Gaps and Opportunities from a Nation-Wide Cohort.

chemotherapy cohort studies epidemiology gallbladder neoplasms surgery

Journal

Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829

Informations de publication

Date de publication:
09 Apr 2020
Historique:
received: 09 03 2020
revised: 31 03 2020
accepted: 03 04 2020
entrez: 15 4 2020
pubmed: 15 4 2020
medline: 15 4 2020
Statut: epublish

Résumé

Gallbladder cancer (GBC) is rare in Western populations and data about treatment and outcomes are scarce. This study aims to analyze survival and identify opportunities for improvement using population-based data from a low-incidence country. GBC patients diagnosed between 2005 and 2016 with GBC were identified from the Netherlands Cancer Registry. Patients were grouped according to time period (2005-2009/2010-2016) and disease stage. Trends in treatment and overall survival (OS) were analyzed. In total 1834 patients were included: 661 (36%) patients with resected, 278 (15%) with non-resected non-metastatic, and 895 (49%) with metastatic GBC. Use of radical versus simple cholecystectomy (12% vs. 26%,

Identifiants

pubmed: 32283627
pii: cancers12040918
doi: 10.3390/cancers12040918
pmc: PMC7226578
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : ADP
ID : 55695817

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Auteurs

Elise de Savornin Lohman (E)

Department of Surgery, Radboud University Medical Centre, 6500 HB Nijmegen, The Netherlands.

Tessa de Bitter (T)

Department of Pathology, Radboud University Medical Centre, 6500 HB Nijmegen, The Netherlands.

Rob Verhoeven (R)

Department of Surgery, Radboud University Medical Centre, 6500 HB Nijmegen, The Netherlands.
Department of Research, Netherlands Comprehensive Cancer Organization, 3501 DB Utrecht, The Netherlands.

Lydia van der Geest (L)

Department of Research, Netherlands Comprehensive Cancer Organization, 3501 DB Utrecht, The Netherlands.

Jeroen Hagendoorn (J)

Department of Surgery, Utrecht University Medical Center, 3508 GA Utrecht, The Netherlands.

Nadia Haj Mohammad (N)

Department of Medical Oncology, Utrecht University Medical Center, Utrecht University, 3508 GA Utrecht, The Netherlands.

Freek Daams (F)

Department of Surgery, Amsterdam University Medical Centers, VU University, Cancer Center Amsterdam, 1007 MB Amsterdam, The Netherlands.

Heinz-Josef Klümpen (HJ)

Department of Medical Oncology, Amsterdam University Medical Centers, University of Amsterdam, Cancer Center Amsterdam, 1100 DD Amsterdam, The Netherlands.

Thomas van Gulik (T)

Department of Surgery, Amsterdam University Medical Centers, University of Amsterdam, Cancer Center Amsterdam, 1100DD Amsterdam, The Netherlands.

Joris Erdmann (J)

Department of Surgery, Amsterdam University Medical Centers, University of Amsterdam, Cancer Center Amsterdam, 1100DD Amsterdam, The Netherlands.

Marieke de Boer (M)

Department of Surgery, Section of HPB-Surgery and Liver Transplantation, University Medical Center Groningen, 97700 RB Groningen, The Netherlands.

Frederik Hoogwater (F)

Department of Surgery, Section of HPB-Surgery and Liver Transplantation, University Medical Center Groningen, 97700 RB Groningen, The Netherlands.

Bas Groot Koerkamp (BG)

Department of Surgery, Erasmus MC, 3000 CB Rotterdam, The Netherlands.

Andries Braat (A)

Department of Surgery, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.

Joanne Verheij (J)

Department of Pathology, Amsterdam University Medical Center, 1100 DD Amsterdam, The Netherlands.

Iris Nagtegaal (I)

Department of Pathology, Radboud University Medical Centre, 6500 HB Nijmegen, The Netherlands.

Cornelis van Laarhoven (C)

Department of Surgery, Radboud University Medical Centre, 6500 HB Nijmegen, The Netherlands.

Peter van den Boezem (P)

Department of Surgery, Radboud University Medical Centre, 6500 HB Nijmegen, The Netherlands.

Rachel van der Post (R)

Department of Pathology, Radboud University Medical Centre, 6500 HB Nijmegen, The Netherlands.

Philip de Reuver (P)

Department of Surgery, Radboud University Medical Centre, 6500 HB Nijmegen, The Netherlands.

Classifications MeSH