An unusual variant of lichen nitidus: Generalized follicular spinous with perifollicular granulomas.


Journal

Journal of cutaneous pathology
ISSN: 1600-0560
Titre abrégé: J Cutan Pathol
Pays: United States
ID NLM: 0425124

Informations de publication

Date de publication:
Sep 2020
Historique:
received: 12 01 2020
revised: 14 03 2020
accepted: 10 04 2020
pubmed: 15 4 2020
medline: 22 6 2021
entrez: 15 4 2020
Statut: ppublish

Résumé

Several unusual variants of lichen nitidus are described in the literature. Spinous follicular lichen nitidus with perifollicular granulomas is one such variant characterized by generalized follicular as well as nonfollicular keratotic papules, which show perifollicular granulomas on histopathology as well as a lichenoid granulomatous tissue reaction typical of lichen nitidus. Owing to its atypical clinical and histopathologic manifestations, it raises several clinical possibilities and can be a diagnostic challenge. We report this rare variant of lichen nitidus in a 19-year-old female, and discuss its clinical and histopathological differential diagnosis.

Identifiants

pubmed: 32285461
doi: 10.1111/cup.13712
doi:

Substances chimiques

Antimalarials 0
Glucocorticoids 0
Dapsone 8W5C518302
Prednisolone 9PHQ9Y1OLM

Types de publication

Case Reports

Langues

eng

Sous-ensembles de citation

IM

Pagination

834-839

Informations de copyright

© 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Références

Lapins NA, Willoughby C, Helwig EB. Lichen nitidus. a study of forty-three cases. Cutis. 1978;21(5):634-637.
Macdonald AJ, Drummond A, Chui D, Holmes S. Lichen nitidus and lichen spinulosus or spinous follicular lichen nitidus? Clin Exp Dermatol. 2005;30(4):452-453.
Madhok R, Winkelmann RK. Spinous, follicular lichen nitidus associated with perifollicular granulomas. J Cutaneous Pathol. 1988;15(4):245-248.
Summe HS, Greenlaw SM, Deng A, Magro C, Wiss K. Generalized spinous follicular lichen nitidus with perifollicular granulomas. Pediatr Dermatol. 2013;30(3):e20-e21.
Sanders S, Collier DA, Scott R, Wu H, McNutt NS. Periappendageal lichen nitidus: report of a case. J Cutan Pathol. 2002;29(2):125-128.
Deza G, Gallardo F, Barranco C, Marques L, Pujol RM. Disseminated granulomatous perifollicular dermatosis with comedones: a follicular variant of lichen Nitidus or a new entity? Am J Dermatopathol. 2018;40(9):694-698.
Park JS. Lichen nitidus and lichen spinulosus or spinous follicular lichen nitidus? a second case. Clin Exp Dermatol. 2011;36(5):557-558.
Khandpur S, Kathuria SD, Gupta R, Singh MK, Sharma VK. Hyperkeratotic pitted plaques on the palms and soles. Indian J Dermatol Venereol Leprol. 2010;76(1):52-55.
Singhal P, Patel PH, Marfatia YS. Lichen scrofulosorum: a diagnosis overlooked. Indian Dermatol Online J. 2012;3(3):190-192.
Ilkit M, Durdu M, Karakas M. Majocchi's granuloma: a symptom complex caused by fungal pathogens. Med Mycol. 2012;50(5):449-457.
Hruza GJ, Posnick RB, Weltman RE. Disseminated lupus vulgaris presenting as granulomatous folliculitis. Int J Dermatol. 1989;28(6):388-392.
vanDoorn R, Scheffer E, Willemze R. Follicular mycosis fungoides, a distinct disease entity with or without associated follicular mucinosis: a clinicopathologic and follow-up study of 51 patients. Arch Dermatol. 2002;138(2):191-198.
Flaig MJ, Cerroni L, Schuhmann K, et al. Follicular mycosis fungoides: a clinicopathologic analysis of nine cases. J Cutan Pathol. 2001;28(10):525-530. https://doi.org/10.1034/j.1600-0560.2001.281006.x.
Rajalakshmi T, Inchara YK, Antony M. Follicular mycosis fungoides - a report of four Indian cases. Indian J Med Paediatr Oncol. 2009;30(3):108-112. https://doi.org/10.4103/0971-5851.6425.

Auteurs

Neha Taneja (N)

Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India.

Nikhil Mehta (N)

Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India.

Sudheer Arava (S)

Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.

Vishal Gupta (V)

Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India.

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